LSBio
KLF2 Antibody (aa216-265)

Anti-KLF2 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

KLF2 Antibody (aa216-265)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$470.00each
Catalog Number: LS-B4570-50

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Overview

Description
KLF2 antibody LS-B4570 is an unconjugated rabbit polyclonal antibody to human KLF2 (aa216-265). Validated for IHC and WB. Cited in 4 publications.
Application
IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Krueppel-like factor 2 | Kruppel-like factor LKLF | Kruppel-like factor 2 (lung) | Lung krueppel-like factor | LKLF | KLF2
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
0.2 - 1 µg/ml
UniProt Number
Q9Y5W3
SwissProt
Q9Y5W3

Target

Target
KLF2
Antigen Species
Human
Specificity
Human KLF2
Epitope
Human KLF2
Gene Name
KLF2

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide located between aa216-265 of human KLF2 (Q9Y5W3, NP_057354). Percent identity by BLAST analysis: Human, Chimpanzee, Gibbon, Monkey, Galago, Pig (100%); Marmoset, Mouse, Rat, Opossum, Guinea pig, Platypus (92%); Xenopus (90%); Salmon (85%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% sodium azide, 2% sucrose
Concentration
0.5 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS

SIV/SHIV Infection Triggers Vascular Inflammation, Diminished Expression of Krüppel-like Factor 2 and Endothelial Dysfunction. Panigrahi S, Freeman ML, Funderburg NT, Mudd JC, Younes SA, Sieg SF, Zidar DA, Paiardini M, Villinger F, Calabrese LH, Ransohoff RM, Jain MK, Lederman MM. The Journal of infectious diseases. 2016 May;213:1419-27.

PubMed: 26671887 · PMC: PMC4813739


Integrated proteomics and metabolomics analysis reveals differential lipid metabolism in human umbilical vein endothelial cells under high and low shear stress. Gabriela Venturini, Pamella Araujo Malagrino, Kallyandra Padilha, Leonardo Yuji Tanaka, Francisco Rafael Laurindo, Rafael Dariolli, Valdemir Melechco Carvalho, Karina Helena Morais Cardozo, Jose Eduardo Krieger, Alexandre da Costa Pereira. American journal of physiology. Cell physiology. 2019 August;317:C326-C338.

PubMed: 31067084


SARS-CoV-2 Spike Protein Destabilizes Microvascular Homeostasis. Soumya Panigrahi, Tamal Goswami, Brian Ferrari, Christopher J Antonelli, Douglas A Bazdar, Hannah Gilmore, Michael L Freeman, Michael M Lederman, Scott F Sieg. Microbiology spectrum. 2021 December;9:e0073521.

PubMed: 34935423 · PMC: PMC8693925


Human ß-Defensin-3 is Associated With Platelet-Derived Extracellular Vesicles and is a Potential Contributor to Endothelial Dysfunction. Soumya Panigrahi, Santosh K Ghosh, Brian Ferrari, Jonathan M Wyrick, Eugene A Podrez, Aaron Weinberg, Scott F Sieg. Frontiers in molecular biosciences. 2022 April;9:824954.

PubMed: 35355507 · PMC: PMC8959671

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