LSBio
JUP/CTNNG/Junction Plakoglobin Antibody (aa45-114)

JUP/CTNNG/Junction Plakoglobin Antibody (aa45-114)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunofluorescence, Immunohistochemistry (general), Immunoprecipitation, Western Blot
Reactivity:Human
Format:Liquid
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$818.00each
Catalog Number: LS-C21269-100

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Overview

Description
Junction Plakoglobin antibody LS-C21269 is an unconjugated mouse monoclonal antibody to human Junction Plakoglobin (JUP / CTNNG) (aa45-114). Validated for IF, IP and WB. Cited in 1 publication.
Application
IF, IHC, IP, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Desmoplakin-3 | CTNNG | DPIII | Gamma catenin | Junction plakoglobin | JUP | PKGB | ARVD12 | Catenin gamma | Desmoplakin III | DP3 | PDGB
Recommended Dilution: IF/ICC
10 ug/ml
UniProt Number
P14923
NCBI GenBank
NM_002230 | NP_002221.1
SwissProt
P14923

Target

Target
Human JUP/CTNNG/Junction Plakoglobin
Antigen Species
Human
Epitope
Specific for human and mouse plakoglobin (~83kD) and does not appear to cross-react with the related b-catenin protein (~92kD). The immunoreactive epitope has been localized to a site between amino acids 45-114 of the human plakoglobin protein.
Gene Name
JUP

Antibody

Host Species
Mouse
Clonality
Monoclonal
Isotype
IgG1
Light Chain
Kappa Light Chain

Immunogen

Immunogen
Fusion protein consisting of the maltose binding protein fused to full length human plakoglobin protein.
Immunogen Type
Fusion Protein (e.g., GST, MBP tag)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.2, 0.1% Sodium Azide
Preservative
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Antibody phage display assisted identification of junction plakoglobin as a potential biomarker for atherosclerosis. Cooksley-Decasper S, Reiser H, Thommen DS, Biedermann B, Neidhart M, Gawinecka J, Cathomas G, Franzeck FC, Wyss C, Klingenberg R, Nanni P, Roschitzki B, Matter C, Wolint P, Emmert MY, Husmann M, Amann-Vesti B, Maier W, Gay S, Lüscher TF, von Eckardstein A. PloS one. 2012;7:e47985. PubMed: 23110151 PMC: PMC3480477
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