LSBio
ITGB4 / Integrin Beta 4 Antibody

Positive WB detected in:Mouse brain tissue;All lanes:ITGB4 antibody at 3.5ug/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 203,196,201,195,107 kDa;Observed band size: 203 kDa;

ITGB4 / Integrin Beta 4 Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Western Blot
Reactivity:Human, Mouse
Format:Liquid
See all Human ITGB4 / Integrin Beta 4 antibodies →
$300.00each
Catalog Number: LS-C499158-50

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Overview

Description
Integrin Beta 4 antibody LS-C499158 is an unconjugated rabbit polyclonal antibody to Integrin Beta 4 (ITGB4) from human. It is reactive with human and mouse. Validated for ELISA, IF, IHC and WB.
Application
ELISA, IF, IHC, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CD104 | Integrin beta-4 | Integrin Beta 4 | gp150 | ITGB4 | CD104 antigen | Integrin beta-4 subunit | Integrin, beta 4
UniProt Number
P16144
SwissProt
P16144

Target

Target
Human ITGB4 / Integrin Beta 4
Antigen Species
Human
Epitope
Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760).
Gene Name
ITGB4

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
Recombinant Human Integrin beta-4 protein (1401-1533AA)
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

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