ITGAM / CD11b Antibody (clone X-5, Biotin)

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Antibody:	Mouse Monoclonal
Applications:	Immunohistochemistry (general), Immunohistochemistry, Frozen
Reactivity:	Human
Format:	Lyophilized

$630.00each

Catalog Number: LS-C96240-750

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Description: CD11b antibody LS-C96240 is a biotin-conjugated mouse monoclonal antibody to human CD11b (ITGAM). Validated for IHC.
Application: IHC, IHC-F
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain | ITGAM
Recommended Dilution: IHC-F: 1:100 - 1:200
UniProt Number: P11215
NCBI GenBank: NM_000632 | NP_000623.2
SwissProt: P11215

Target: Human ITGAM / CD11b
Antigen Species: Human
Epitope: The antigen is CD11b, the epitope has not been further characterized. Antigen distribution: Isolated cells: Weakly positive on granulocytes, positive on peritoneal macrophages, negative on lymphocytes. Positive on HL-60 cells , particularly after DMSO treatment. Tissue sections: In lymph nodes, monoclonal antibody X-5 is positive on monocytes, macrophages and single cells both intrafollicularly and in surrounding blood vessels. Positive staining has been observed with the basal membrane of blood vessels and on sinus walls. Marginal zone macrophages, medulla and red pulp stain positive in the spleen as do cells in the T-cell region. In the thymus, medulla and trabecular macrophages are positive. Specificity: Human: granulocytes, monocytes, (NK- cells). Other: not tested.
Gene Name: ITGAM

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