ITGAM / CD11b Antibody (clone M1/70.15, RPE)
Primary AntibodyLSBio Guarantee
| Antibody: | Rat Monoclonal |
| Applications: | Flow Cytometry |
| Reactivity: | Mouse |
| Format: | Lyophilized |
$413.00each
Catalog Number: LS-C45336-100
Catalog Number: LS-C45336
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- Description
- CD11b antibody LS-C45336 is an RPE-conjugated rat monoclonal antibody to mouse CD11b (ITGAM). Validated for Flow.
- Application
- FC
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain | ITGAM
- Recommended Dilution: FC
- 1:1 - 1:10
- UniProt Number
- P11215
- NCBI GenBank
- NM_000632 | NP_000623.2
- SwissProt
- P11215
Target
- Target
- Mouse ITGAM / CD11b
- Antigen Species
- Mouse
- Epitope
- Recognizes the murine CD11b cell surface antigen (also known as the alpha M integrin chain or MAC-1), a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages. Peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages. Clone M1/70.15 has been reported to block iC3b binding to its receptor. * Clone M1/70.15 has been reported to as being suitable for use on PLP fixed paraffin embedded tissue but has not been tested for use on formalin fixed tissue. This product is routinely tested in flow cytometry on mouse peritoneal macrophages.
- Gene Name
- ITGAM
Antibody
- Host Species
- Rat
- Clonality
- Monoclonal
- Clone
- M1/70.15
- Isotype
- IgG2b
Immunogen
- Immunogen
- T cells enriched splenocytes from B10 mice.
- Immunogen Type
- Cell-Based Immunization
Format
- Conjugate/Label
- Phycoerythrin
- Format
- Lyophilized
- Formulation
- PBS, 0.09% Sodium Azide, 5% Sucrose, 1% BSA
- Preservative
- Yes
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C. Do not freeze. Store undiluted. Protect from light. Microcentrifugation recommended if solution contains precipitate.
- Recommended Storage Buffer
- PBS