LSBio
ITGA5/Integrin Alpha 5/CD49e Antibody (clone X-6, Biotin)

ITGA5/Integrin Alpha 5/CD49e Antibody (clone X-6, Biotin)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Frozen
Reactivity:Human
Format:Lyophilized
See all Human ITGA5/Integrin Alpha 5/CD49e antibodies →
$743.00each
Catalog Number: LS-C96242-100

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Overview

Description
CD49e antibody LS-C96242 is a biotin-conjugated mouse monoclonal antibody to human CD49e (ITGA5 / Integrin Alpha 5). Validated for IHC.
Application
IHC, IHC-F
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
FNRA | Integrin alpha-5 | Integrin Alpha 5 | ITGA5 | Integrin alpha-F | VLA-5 | CD49e | CD49e antigen | VLA5A
Recommended Dilution: IHC-F
1:100
UniProt Number
P08648
NCBI GenBank
NM_002205 | NP_002196.2
SwissProt
P08648

Target

Target
Human ITGA5/Integrin Alpha 5/CD49e
Antigen Species
Human
Epitope
The antigen is a 154-180kDa protein as determined by immunoprecipitation. The epitope has not been further characterized. Antigen distribution: Isolated cells: Granulocytes, monocytes; positive on blood monocyte-derived macrophages days 0-28. Dull staining with 95% cord blood CD34+ cells, weak reaction on resting neutrophils. Staining increases with maturation of granulocytes. Treatment with fMLP, TNF, GM-CSF and temperature causes positive shift with granulocytes and monocytes. PMA treatment of granulocytes leads to a decrease in the number of positive cells. Positive with cell lines U937, DH39 & MEP, HL-60, NB4, HMC-1. Tissue sections: X-6 is positive on lining cells in different infiltrations and endothelial cells in the synovial membrane of rheumatoid arthritis patients. The staining pattern is similar to CD34 in these patients. Specificity: Human: granulocytes, monocytes, platelets. Other species: not tested.
Gene Name
ITGA5

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
X-6
Origin Species
Human

Immunogen

Immunogen
Human monocytes
Immunogen Type
Cell-Based Immunization

Format

Conjugate/Label
Biotin
Format
Lyophilized
Formulation
Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C.
Recommended Storage Buffer
PBS

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To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.