ITGA2B / CD41 Antibody (clone M148)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Frozen, Immunoprecipitation |
| Reactivity: | Human |
| Format: | Liquid |
$492.00each
Catalog Number: LS-C827866-0.1
Catalog Number: LS-C827866
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- Description
- CD41 antibody LS-C827866 is an unconjugated mouse monoclonal antibody to human CD41 (ITGA2B). Validated for Flow, ICC, IF, IHC and IP.
- Application
- FC, ICC, IF, IHC-F, IP
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- BDPLT2 | CD41B | GT | gp2B | Integrin alpha-IIb | ITGA2B | ITGAB | GPIIb | HPA3 | Platelet-specific antigen BAK | CD41 | CD41 antigen | GPalpha IIb | GTA
- UniProt Number
- P08514
- NCBI GenBank
- NM_000419 | NP_000410.2
- SwissProt
- P08514
Target
- Target
- Human ITGA2B / CD41
- Antigen Species
- Human
- Epitope
- This antibody recognizes integrin alpha 2b, a 110-130 kDa transmembrane protein that is also known as CD41. CD41 associates with the integrin CD61 to form the CD41/CD61 (GPIIb/IIIa) heterodimer, a fibronectin receptor expressed in platelets. The antibody M148 binds to some medulloblastoma and neuroblastoma cells and rhabdomyosarcoma and certain other solid tumors. No binding is observed to marrow constituents other than platelets and megakaryocytes. The antibody M148 prevents aggregation of platelets.
- Gene Name
- ITGA2B
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- M148
- Isotype
- IgG1
- Origin Species
- Human
Immunogen
- Immunogen
- Homogenized human medulloblastoma tissue.
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS, 0.09% Sodium Azide
- Concentration
- 1 mg/mL
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS