IRF3 Antibody (aa108-166, clone 3F10)

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Antibody:	Mouse Monoclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunoprecipitation, Western Blot
Reactivity:	Human
Format:	Liquid

$442.00each

Catalog Number: LS-C45030-0.1

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Description: IRF3 antibody LS-C45030 is an unconjugated mouse monoclonal antibody to human IRF3 (aa108-166). Validated for ELISA, IP and WB.
Application: ELISA, IP, WB
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names: Interferon regulatory factor 3 | IRF-3 | IRF3
Recommended Dilution: WB: 1:2000 - 1:3000
UniProt Number: Q14653
NCBI GenBank: NM_001571 | NP_001562.1
SwissProt: Q14653

Target: Human IRF3
Antigen Species: Human
Epitope: Recognizes human interferon regulatory factor 3 (IRF3), a 55kD constitutively expressed member of the IRF family, which acts as vital regulator of gene expression in innate immunity. IRF3 accumulates in an inactive form in the cytoplasm and then translocates to the nucleus as a homodimer, following stimuli-induced phosphorylation of specific serine/threonine residues. Association of the homodimer with p300/CBP (CREBB binding protein) forms dsRNA-activated factor 1 (DRAF1), which then activates the transcription of interferon alpha and beta, along with other interferon-induced genes.
Gene Name: IRF3

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS