IMP-3 / IGF2BP3 Antibody (HRP)

Primary AntibodyLSBio Guarantee

Antibody:	Rabbit Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay
Reactivity:	Human
Format:	Liquid

$300.00each

Catalog Number: LS-C499125-50

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Description: IGF2BP3 antibody LS-C499125 is an HRP-conjugated rabbit polyclonal antibody to human IGF2BP3 (IMP-3). Validated for ELISA.
Application: ELISA
Reactivity: Hu
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: CT98 | IGF II mRNA binding protein 3 | IMP-3 | KOC1 | IGF-II mRNA-binding protein 3 | IGF2 mRNA-binding protein 3 | IGF2BP3 | VICKZ family member 3 | Cancer/testis antigen 98 | HKOC | VICKZ3
UniProt Number: O00425
NCBI GenBank: NM_006547 | NP_006538.2
SwissProt: O00425

Target: Human IMP-3 / IGF2BP3
Antigen Species: Human
Epitope: RNA-binding factor that may recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3'-UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation in cancer cells. Binds to beta-actin/ACTB and MYC transcripts. Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.
Gene Name: IGF2BP3

Immunogen: Recombinant Human Insulin-like growth factor 2 mRNA-binding protein 3 protein (1-100AA)
Immunogen Type: Recombinant Immunogen

Storage Conditions: Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Recommended Storage Buffer: PBS

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