IL6R / IL6 Receptor Antibody (Extracellular Domain)
Primary AntibodyLSBio Guarantee
| Antibody: | Rat Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Western Blot |
| Reactivity: | Mouse |
| Format: | Lyophilized |
$926.00each
Catalog Number: LS-C70920-100
Catalog Number: LS-C70920
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- Description
- IL6 Receptor antibody LS-C70920 is an unconjugated rat monoclonal antibody to mouse IL6 Receptor (IL6R) (Extracellular Domain). Validated for ELISA and WB. Cited in 1 publication.
- Application
- ELISA, WB
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This antibody carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- CD126 | gp80 | IL-6R subunit alpha | IL-6R-alpha | IL-6RA | IL6Q | IL-6 receptor subunit alpha | IL-6R 1 | IL-6R-1 | Interleukin 6 receptor | Membrane glycoprotein 80 | CD126 antigen | IL6R | IL6RA | IL6RQ
- UniProt Number
- P08887
- NCBI GenBank
- NM_000565 | NP_000556.1
- SwissProt
- P08887
Target
- Target
- Mouse IL6R / IL6 Receptor
- Antigen Species
- Mouse
- Epitope
- Recognizes mouse IL-6Ralpha. In direct ELISAs and Western Blots, this antibody does not cross-react with rhIL-6R.
- Gene Name
- IL6R
Antibody
- Host Species
- Rat
- Clonality
- Monoclonal
- Isotype
- IgG1
Immunogen
- Immunogen
- NS0-derived rmIL-6Ralpha extracellular domain (aa 20-357) P22272
Format
- Conjugate/Label
- Unconjugated
- Format
- Lyophilized
- Formulation
- Lyophilized from PBS, pH 7.4, 5% Trehalose
- Preservative
- No
- Purification Method
- Protein G Affinity
Storage & Handling
- Storage Conditions
- Store at -20°C lyophilized. Once reconstituted: Store at -20°C. Aliquot to avoid freeze-thaw cycles.
- Recommended Storage Buffer
- PBS
Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130. Wang X, Miller EB, Goswami M, Zhang P, Ronning KE, Karlen SJ, Zawadzki RJ, Pugh EN Jr, Burns ME. Journal of neuroinflammation. 2017;14:121. PubMed: 28645275 PMC: PMC5481880