IL1RL1 Antibody (N-Terminal)

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Antibody:	Rabbit Polyclonal
Applications:	Immunohistochemistry (general), Western Blot
Reactivity:	Mouse
Format:	Liquid

$436.00each

Catalog Number: LS-C43164-0.1

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Description: IL1RL1 antibody LS-C43164 is an unconjugated rabbit polyclonal antibody to mouse IL1RL1 (N-Terminal). Validated for WB.
Application: IHC, WB
Reactivity: Ms
Intended Use: Research Use Only
Guarantees: This antibody carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: DER4 | Growth stimulation-expressed | IL33R | Interleukin-1 receptor-like 1 | Interleukin 1 receptor-like 1 | ST2 | ST2L | ST2V | FIT-1 | IL1RL1 | Protein ST2 | ST2 protein | IL-1R4 | IL1R4
UniProt Number: Q01638
NCBI GenBank: NM_016232 | NP_057316.3
SwissProt: Q01638

Target: Mouse IL1RL1
Antigen Species: Mouse
Epitope: Recognizes an epitope within the N-Terminal region (NT) of mouse ST2, a member of the Toll-interleukin 1 receptor (TIR) superfamily, expressed by mast cells and TH2 helper cells, but not by TH1 effector cells. The majority of TIR superfamily members, which includes the Interleukin-1 receptor (IL-1R1), Toll-like receptors (TLRs) and the cytosolic adaptor proteins MyD88, TIRAP, Trif and TRAM, initiate innate immunity through the ultimate activation of the transcription factor NF-kappaB and are inducers of the inflammatory response. In contrast ST2, which itself is unable to activate NF-kappaB, has been identified as a negative regulator of IL-1R1 and TLR4 signaling by sequestering MyD88 and TIRAP in line with its role as a crucial receptor in TH2-cell mediated responses and.
Gene Name: IL1RL1

Immunogen: A 16 AA synthetic peptide located near mouse ST2 N-Terminus. This peptide is common to the three known isoforms of ST2.
Immunogen Type: Synthetic Peptide (Linear)

Storage Conditions: Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Recommended Storage Buffer: PBS