LSBio
IL18 Antibody (aa37-193)

IL18 antibody. IHC(P): Human Tonsil Tissue.

IL18 Antibody (aa37-193)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Lyophilized
See all Human IL18 antibodies →
$480.00each
Catalog Number: LS-C313397-100

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Overview

Description
IL18 antibody LS-C313397 is an unconjugated rabbit polyclonal antibody to human IL18 (aa37-193). Validated for ELISA, IHC and WB. Cited in 2 publications.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This antibody carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
IGIF | IL-1g | Interleukin-18 | IFN-gamma-inducing factor | IL-1 gamma | IL-18 | IL18 | Iboctadekin | IL1F4 | Interleukin-1 gamma
UniProt Number
Q14116
SwissProt
Q14116

Target

Target
Human IL18
Antigen Species
Human
Epitope
aa37-193 of human IL18. No cross reactivity with other proteins
Gene Name
IL18

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
E.coli-derived human IL-18 recombinant protein (Position: Y37-D193). Human IL-18 shares 66% and 64% amino acid (aa) sequences identity with mouse and rat IL-18, respectively.
Immunogen Type
Recombinant Immunogen

Format

Conjugate/Label
Unconjugated
Format
Lyophilized
Formulation
Lyophilized from 0.2mg Na2HPO4, 5mg BSA, 0.9mg NaCl, 0.05mg sodium azide.
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid freeze-thaw cycles.
Recommended Storage Buffer
NaCl

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation. Palazón-Riquelme P, Worboys JD, Green J, Valera A, Martín-Sánchez F, Pellegrini C, Brough D, López-Castejón G. EMBO reports. 2018 October;19:pii e44766.

PubMed: 30206189 · PMC: PMC6172458


Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro. Anna Gritsenko, Shi Yu, Fatima Martin-Sanchez, Ines Diaz-Del-Olmo, Eva-Maria Nichols, Daniel M Davis, David Brough, Gloria Lopez-Castejon. Frontiers in immunology. 2020 October;11:565924.

PubMed: 33101286 · PMC: PMC7555430

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