LSBio
IHC-plus™ WNT16 Antibody (Internal)

Anti-WNT16 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ WNT16 Antibody (Internal)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
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$449.00each
Catalog Number: LS-A9630-50

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Overview

Description
WNT16 antibody LS-A9630 is an unconjugated rabbit polyclonal antibody to human WNT16 (Internal). Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Application
IHC, IHC-P
Reactivity
Hu
Predicted Reactivity
Bovine, Horse, Non-Human Primate
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
WNT16 | Protein Wnt-16
Recommended Dilution: IHC-P
5 µg/ml
UniProt Number
Q9UBV4
SwissProt
Q9UBV4

Target

Target
WNT16
Antigen Species
Human
Specificity
Human WNT16. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Epitope
Human WNT16. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Gene Name
WNT16

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 15 amino acid peptide from internal region of human WNT16. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Marmoset, Bovine, Horse (93%); Hamster, Elephant, Pig (87%); Mouse, Rat, Panda, Dog, Bat, Rabbit, Lizard (80%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

WNT16B is a new marker of cellular senescence that regulates p53 activity and the phosphoinositide 3-kinase/AKT pathway. Binet R, Ythier D, Robles AI, Collado M, Larrieu D, Fonti C, Brambilla E, Brambilla C, Serrano M, Harris CC, Pedeux R. Cancer research. 2009 Dec;69:9183-91.

PubMed: 19951988


Lysyl oxidase activity regulates oncogenic stress response and tumorigenesis. Wiel C, Augert A, Vincent DF, Gitenay D, Vindrieux D, Le Calv[Character e9] B, Arfi V, Lallet-Daher H, Reynaud C, Treilleux I, Bartholin L, Lelievre E, Bernard D. Cell death & disease. 2013;4:e855.

PubMed: 24113189 · PMC: PMC3824691


Carriers of a novel frame-shift insertion in WNT16a possess elevated pancreatic expression of TCF7L2. Howard EW, Been LF, Lerner M, Brackett D, Lightfoot S, Bullen EC, Sanghera DK. BMC genetics. 2013;14:28.

PubMed: 23617586 · PMC: PMC3675375

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