LSBio
IHC-plus™ UMOD / Uromodulin Antibody (clone 10.32, FITC)

Anti-UMOD / Uromodulin antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ UMOD / Uromodulin Antibody (clone 10.32, FITC)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin
Reactivity:Dog, Human
Format:Liquid
See all UMOD / Uromodulin antibodies →
$470.00each
Catalog Number: LS-B3105-50

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Overview

Description
Uromodulin antibody LS-B3105 is an FITC-conjugated mouse monoclonal antibody to Uromodulin (UMOD) from human. It is reactive with human and dog. Validated for ELISA, IF and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Application
ELISA, IF, IHC, IHC-F, IHC-P
Reactivity
Can, Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
ADMCKD2 | FJHN | HNFJ | MCKD2 | THGP | THP | Uromucoid | Tamm-Horsfall glycoprotein | HNFJ1 | UMOD | Uromodulin
Recommended Dilution: IHC-P
1:50
UniProt Number
P07911
SwissProt
P07911

Target

Target
UMOD / Uromodulin
Antigen Species
Human
Specificity
Anti-human Tamm-Horsfall protein (THP) is a monoclonal antibody which reacts with an epitope of the urinary mucoprotein. Tamm-Horsfall protein is a glycoprotein of approximately 80 kD containing up to 25% carbohydrate by weight.
Epitope
Anti-human Tamm-Horsfall protein (THP) is a monoclonal antibody which reacts with an epitope of the urinary mucoprotein. Tamm-Horsfall protein is a glycoprotein of approximately 80 kD containing up to 25% carbohydrate by weight.
Gene Name
UMOD

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
10.32
Origin Species
Human

Immunogen

Immunogen
Human Tamm-Horsfall protein

Format

Conjugate/Label
Fluorescein Isothiocyanate
Format
Liquid
Formulation
PBS, 0.02% Sodium Azide, BSA
Concentration
0.1 mg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.
Recommended Storage Buffer
PBS

Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study. Jayachandran M, Lugo G, Heiling H, Miller VM, Rule AD, Lieske JC. Biology of sex differences. 2015;6:2.

PubMed: 25729563 · PMC: PMC4345020


Specific renal parenchymal-derived urinary extracellular vesicles identify age-associated structural changes in living donor kidneys. Turco AE, Lam W, Rule AD, Denic A, Lieske JC, Miller VM, Larson JJ, Kremers WK, Jayachandran M. Journal of Extracellular Vesicles. 2016;5:29642.

PubMed: 26837814 · PMC: PMC4737715


Urinary extracellular vesicle-associated MCP-1 and NGAL derived from specific nephron segments differ between calcium oxalate stone formers and controls. Robin S Chirackal, Muthuvel Jayachandran, Xiangling Wang, Samuel Edeh, Zejfa Haskic, Majuran Perinpam, Timothy M Halling, Ramila Mehta, Marcelino E Rivera, John C Lieske. American journal of physiology. Renal physiology. 2019 December;317:F1475-F1482.

PubMed: 31461349 · PMC: PMC6962507

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