Tuberin / TSC2 Antibody
Catalog Number: LS-C10889-200
200 µL / $763.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunoprecipitation, Western Blot
Reactivity: Human
Format: Liquid
Anti-TSC2 / Tuberin antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
IHC-plus™ Tuberin / TSC2 Antibody (phospho-Ser664)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Human |
| Format: | Liquid |
$383.00each
Catalog Number: LS-B1654-50
Catalog Number: LS-B1654
For bulk orders or custom formulations:
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- Description
- TSC2 antibody LS-B1654 is an unconjugated rabbit polyclonal antibody to human TSC2 (Tuberin) (pSer664). Validated for ICC, IF and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
- Application
- ICC, IF, IHC, IHC-P
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- LAM | Tuberous sclerosis 2 protein | TSC4 | Tuberin | Tuberous sclerosis 2 | TSC2
- Recommended Dilution: IHC-P
- 1:50
- UniProt Number
- P49815
- NCBI GenBank
- NM_000548 | NP_000539.2
- SwissProt
- P49815
Target
- Target
- Tuberin / TSC2
- Antigen Species
- Human
- Specificity
- Modified peptide
- Epitope
- Modified peptide
- Gene Name
- TSC2
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Synthetic peptide from human TSC2.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol.
- Concentration
- 0.35 mg/mL
- Volume
- 50 Microliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- Phosphate-buffered
Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic beta-cell proliferation. Bartolom A, Guilln C, Benito M. Endocrinology. 2010;151:3084-94.
PubMed: 20427478
Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling. Miyazaki M, McCarthy JJ, Fedele MJ, Esser KA. The Journal of physiology. 2011;589:1831-46.
PubMed: 21300751 · PMC: PMC3099033
