LSBio
IHC-plus™ TRPM2 Antibody (aa1139-1150)

Anti-TRPM2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.

IHC-plus™ TRPM2 Antibody (aa1139-1150)

Primary AntibodyLSBio Guarantee
Antibody:Goat Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Human, Non-Human Primate
Format:Liquid
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$495.00each
Catalog Number: LS-B4122-50

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Overview

Description
TRPM2 antibody LS-B4122 is an unconjugated goat polyclonal antibody to TRPM2 (aa1139-1150) from human. It is reactive with human and monkey. Validated for IF, IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IF, IHC, IHC-P
Reactivity
Hu, NHP
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
EREG1 | LTrpC-2 | LTRPC2 | NUDT9L1 | KNP3 | NUDT9H | TRPM2 | Trrp7
Recommended Dilution: IF/ICC
10 µg/ml
Recommended Dilution: IHC-P
3.75 µg/ml
UniProt Number
O94759
SwissProt
O94759

Target

Target
TRPM2
Antigen Species
Human
Specificity
Human TRPM2.
Epitope
Human TRPM2.
Gene Name
TRPM2

Antibody

Host Species
Goat
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Peptide with sequence C-QQKQRPEQKIED, from the internal region of the protein sequence according to NP_003298.1NP_001307279.1NP_001307280.1.
Immunogen Type
Peptide

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
TBS
TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells. Tseng HH, Vong CT, Kwan YW, Lee SM, Hoi MP. Scientific reports. 2016;6:35016. PubMed: 27731349 PMC: PMC5059733

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