Anti-TRPM2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.

IHC-plus™ TRPM2 Antibody (aa1139-1150)

Primary AntibodyLSBio Guarantee

Antibody:	Goat Polyclonal
Applications:	Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:	Human, Non-Human Primate
Format:	Liquid

$495.00each

Catalog Number: LS-B4122-50

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Overview

Description: TRPM2 antibody LS-B4122 is an unconjugated goat polyclonal antibody to TRPM2 (aa1139-1150) from human. It is reactive with human and monkey. Validated for IF, IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application: ELISA, IF, IHC, IHC-P
Reactivity: Hu, NHP
Intended Use: Research Use Only
Guarantees: This product carries the LSBio 100% Guarantee. ✓
Category: Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names: EREG1 | LTrpC-2 | LTRPC2 | NUDT9L1 | KNP3 | NUDT9H | TRPM2 | Trrp7
UniProt Number: O94759
NCBI GenBank: NM_003307 | NP_003298.1
SwissProt: O94759

Recommended Dilution

Application	Dilution
IF/ICC	10 µg/ml
IHC-P	3.75 µg/ml

Target

Target: TRPM2
Antigen Species: Human
Specificity: Human TRPM2.
Epitope: Human TRPM2.
Gene Name: TRPM2

Antibody

Host Species: Goat
Clonality: Polyclonal
Origin Species: Human

Immunogen

Immunogen: Peptide with sequence C-QQKQRPEQKIED, from the internal region of the protein sequence according to NP_003298.1NP_001307279.1NP_001307280.1.
Immunogen Type: Peptide

Format

Conjugate/Label: Unconjugated
Format: Liquid
Formulation: TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Concentration: 0.5 mg/mL
Animal Free: No
Carrier-Free: No
Preservative: Yes
Purification Method: Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer: TBS

TRPM2 regulates TXNIP-mediated NLRP3 inflammasome activation via interaction with p47 phox under high glucose in human monocytic cells. Tseng HH, Vong CT, Kwan YW, Lee SM, Hoi MP. Scientific reports. 2016;6:35016. PubMed: 27731349 PMC: PMC5059733

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