TGFB4 / LEFTY2 Antibody
Catalog Number: LS-C356684-400
400 µL / $401.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Western Blot
Reactivity: Human, Mouse
Format: Liquid
Anti-LEFTY2 antibody IHC of human uterus, myometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
IHC-plus™ TGFB4 / LEFTY2 Antibody (clone 7C5G1H6H10)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$526.00each
Catalog Number: LS-B2540-50
Catalog Number: LS-B2540
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- Description
- LEFTY2 antibody LS-B2540 is an unconjugated mouse monoclonal antibody to human LEFTY2 (TGFB4). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
- Application
- ELISA, IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- EBAF | LEFTYA | Protein lefty-2 | LEFTA | LEFTY2 | TGFB4 | Protein lefty-A | TGF-beta-4
- Recommended Dilution: ELISA
- 1:5000
- Recommended Dilution: IHC-P
- 10 µg/ml
- Recommended Dilution: WB
- 1:2000
- UniProt Number
- O00292
- NCBI GenBank
- NM_003240 | NP_003231.2
- SwissProt
- O00292
Target
- Target
- TGFB4 / LEFTY2
- Antigen Species
- Human
- Specificity
- Reacts with a 30 kDa protein corresponding to human LEFTY. No reactivity occurs against 6X HIS tag. Significant sequence homology exists between the human and mouse forms of LEFTY. Cross reactivity is expected with mouse and rat forms of the protein. Reactivity with other sources has not been determined.
- Epitope
- Reacts with a 30 kDa protein corresponding to human LEFTY. No reactivity occurs against 6X HIS tag. Significant sequence homology exists between the human and mouse forms of LEFTY. Cross reactivity is expected with mouse and rat forms of the protein. Reactivity with other sources has not been determined.
- Gene Name
- LEFTY2
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 7C5G1H6H10
- Light Chain
- Kappa Light Chain
- Origin Species
- Human
Immunogen
- Immunogen
- A BALB/c mouse was immunized with a recombinant form of 6X HIS tagged human LEFTY.
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- 0.02 M Potassium Phosphate, pH 7.2, 0.15 M NaCl, 0.01% Sodium Azide
- Concentration
- 1 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Protein A Affinity
Storage & Handling
- Storage Conditions
- Store at 4°C or -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- 0.02 M Potassium Phosphate, 0.15 M NaCl
Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1. Tsukui T, Capdevila J, Tamura K, Ruiz-Lozano P, Rodriguez-Esteban C, Yonei-Tamura S, Magalln J, Chandraratna RA, Chien K, Blumberg B, Evans RM, Belmonte JC. Proceedings of the National Academy of Sciences of the United States of America. 1999;96:11376-81.
PubMed: 10500184 · PMC: PMC18041
Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor. Ulloa L, Tabibzadeh S. The Journal of biological chemistry. 2001;276:21397-404.
PubMed: 11278746
