LSBio
IHC-plus™ SLC12A4 / KCC1 Antibody (aa997-1007)

Anti-SLC12A4 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ SLC12A4 / KCC1 Antibody (aa997-1007)

Primary AntibodyLSBio Guarantee
Antibody:Goat Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Dog, Hamster, Human, Mammal (Other), Mouse, Rat
Format:Liquid
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$495.00each
Catalog Number: LS-B2377-50

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Overview

Description
KCC1 antibody LS-B2377 is an unconjugated goat polyclonal antibody to KCC1 (SLC12A4) (aa997-1007) from human. It is reactive with human, mouse, rat and other species. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Can, Ham, Hu, Mml, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Erythroid K-Cl cotransporter 1 | HKCC1 | KCC1 | K-Cl cotransporter | SLC12A4 | Erythroid K:Cl cotransporter
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
0.3 - 1 µg/ml
UniProt Number
Q9UP95
SwissProt
Q9UP95

Target

Target
SLC12A4 / KCC1
Antigen Species
Human
Specificity
Human SLC12A4.
Epitope
Human SLC12A4.
Gene Name
SLC12A4

Antibody

Host Species
Goat
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Peptide with sequence C-DPSHAPDNFRE, from the internal region of the protein sequence according to NP_005063.1.
Immunogen Type
Peptide

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
TBS
The Zn(2+)-sensing receptor, ZnR/GPR39, upregulates colonocytic Cl(-) absorption, via basolateral KCC1, and reduces fluid loss. Sunuwar L, Asraf H, Donowitz M, Sekler I, Hershfinkel M. Biochimica et biophysica acta. 2017;1863:947-960. PubMed: 28093242 PMC: PMC5557417

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