LSBio
IHC-plus™ Recombinant Monoclonal Rabbit anti-Human CALD1 / Caldesmon Antibody (clone CALD1/1424R, IHC)

Human Kidney, Negative Control Tissue: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ Recombinant Monoclonal Rabbit anti-Human CALD1 / Caldesmon Antibody (clone CALD1/1424R, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Recombinant Monoclonal
Applications:Immunohistochemistry (general)
Reactivity:Human
Format:Liquid
See all CALD1 / Caldesmon antibodies →
$470.00each
Catalog Number: LS-B16232-50

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Overview

Description
Caldesmon antibody LS-B16232 is an unconjugated rabbit recombinant monoclonal antibody to human Caldesmon (CALD1). Validated for IHC. Tested on 20 paraffin-embedded human tissues.
Application
IHC
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Recombinant Antibodies
Alternative Names
CALD1 | Caldesmon | Caldesmon 1 | HCAD | LCAD | H-CAD | NAG22 | CDM | L-CAD
Recommended Dilution: IHC-P
1:100
UniProt Number
Q05682
SwissProt
Q05682

Target

Target
CALD1 / Caldesmon
Antigen Species
Human
Specificity
Recognizes a protein of 150 kDa , which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa ) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa ) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Epitope
Recognizes a protein of 150 kDa , which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa ) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa ) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Gene Name
CALD1

Antibody

Host Species
Rabbit
Clonality
Recombinant Monoclonal
Clone
CALD1/1424R
Origin Species
Human

Immunogen

Immunogen
Recombinant full-length human CALD1 protein. Antigen Molecular Weight: 150 kDa
Immunogen Type
Full-Length Recombinant Protein

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
10 mM PBS, 0.05% BSA, 0.05% Sodium Azide
Concentration
200 µg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Protein A/G Affinity

Storage & Handling

Storage Conditions
Store at 2°C to 8°C for up to 2 years.
Recommended Storage Buffer
10 mM PBS

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.