LSBio
IHC-plus™ PRDM5 Antibody (aa100-200)

Anti-PRDM5 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ PRDM5 Antibody (aa100-200)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$383.00each
Catalog Number: LS-B1982-50

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Overview

Description
PRDM5 antibody LS-B1982 is an unconjugated rabbit polyclonal antibody to human PRDM5 (aa100-200). Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
BCS2 | PFM2 | PR domain containing 5 | PRDM5 | PR domain-containing protein 5
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
1 - 3 µg/ml
UniProt Number
Q9NQX1
SwissProt
Q9NQX1

Target

Target
PRDM5
Antigen Species
Human
Specificity
A portion of amino acids 100-200 of human PRDM5 protein was used as the immunogen.
Epitope
A portion of amino acids 100-200 of human PRDM5 protein was used as the immunogen.
Gene Name
PRDM5

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide from human PRDM5.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.05% Sodium Azide, 0.2% Gelatin
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrab[Character 11b] de Angelis M, Calogero RA, Couchman JR, Lund AH. PLoS genetics. 8:e1002711.

PubMed: 22589746 · PMC: PMC3349747


Methylation and expression of the tumour suppressor, PRDM5 , in colorectal cancer and polyp subgroups. Bond CE, Bettington ML, Pearson SA, McKeone DM, Leggett BA, Whitehall VL. BMC cancer. 2015;15:20.

PubMed: 25613750 · PMC: PMC4318154

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