LSBio
IHC-plus™ Polyclonal Rabbit anti-Mouse DISC1 Antibody (C-Terminus, IHC, WB)

Anti-DISC1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ Polyclonal Rabbit anti-Mouse DISC1 Antibody (C-Terminus, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
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$383.00each
Catalog Number: LS-B2805-50

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Overview

Description
DISC1 antibody LS-B2805 is an unconjugated rabbit polyclonal antibody to DISC1 (C-Terminus) from mouse. It is reactive with human and mouse. Validated for ELISA, IHC and WB. Cited in 2 publications.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
C1orf136 | DISC1 | Disrupted in schizophrenia 1 | KIAA0457 | SCZD9
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
1 µg/ml
UniProt Number
Q9NRI5
SwissProt
Q9NRI5

Target

Target
DISC1
Antigen Species
Mouse
Specificity
synthetic peptide corresponding to C-terminal residues of mouse DISC1 (Disrupted in schizophrenia 1 protein)
Epitope
synthetic peptide corresponding to C-terminal residues of mouse DISC1 (Disrupted in schizophrenia 1 protein)
Gene Name
DISC1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide from mouse DISC1.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.01% Sodium Azide, 50% Glycerol
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice. Lipina TV, Wang M, Liu F, Roder JC. Neuropharmacology. 2012 Mar;62:1252-62.

PubMed: 21376063


Genetic and pharmacological evidence for schizophrenia-related Disc1 interaction with GSK-3. Lipina TV, Kaidanovich-Beilin O, Patel S, Wang M, Clapcote SJ, Liu F, Woodgett JR, Roder JC. Synapse (New York, N.Y.). 2011 March;65:234-48.

PubMed: 20687111 · PMC: PMC4485461

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