LSBio
IHC-plus™ Polyclonal Rabbit anti-Human TRPM4 Antibody (Internal, IHC)

Anti-TRPM4 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ Polyclonal Rabbit anti-Human TRPM4 Antibody (Internal, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general)
Reactivity:Bovine, Human, Mouse, Rat
Format:Liquid
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$403.00each
Catalog Number: LS-A8605-50

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Overview

Description
TRPM4 antibody LS-A8605 is an unconjugated rabbit polyclonal antibody to TRPM4 (Internal) from human. It is reactive with human, mouse, rat and other species. Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
IHC
Reactivity
Bov, Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
HTRPM4 | LTrpC-4 | PFHB1B | Melastatin-4 | TRPM4B | TRPM4 | LTrpC4
Recommended Dilution: IHC-P
2.5 - 5 µg/ml
UniProt Number
Q8TD43
SwissProt
Q8TD43

Target

Target
TRPM4
Antigen Species
Human
Specificity
Human TRPM4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Epitope
Human TRPM4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Gene Name
TRPM4

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 16 amino acid peptide from internal region of human TRPM4. Percent identity with other species by BLAST analysis: Human, Gorilla, Mouse, Rat, Bovine (100%); Gibbon (94%); Panda, Dog (88%); Elephant (81%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.1% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
TRPM4 cation channel mediates axonal and neuronal degeneration in experimental autoimmune encephalomyelitis and multiple sclerosis. Schattling B, Steinbach K, Thies E, Kruse M, Menigoz A, Ufer F, Flockerzi V, Br[Character fc]ck W, Pongs O, Vennekens R, Kneussel M, Freichel M, Merkler D, Friese MA. Nature medicine. 2012 Dec;18:1805-11. PubMed: 23160238

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