LSBio
IHC-plus™ Polyclonal Rabbit anti-Human SYVN1 / HRD1 Antibody (aa586-617, IHC, IF, WB)

Anti-SYVN1 / HRD1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ Polyclonal Rabbit anti-Human SYVN1 / HRD1 Antibody (aa586-617, IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
See all SYVN1 / HRD1 antibodies →
$470.00each
Catalog Number: LS-B3451-200

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Overview

Description
HRD1 antibody LS-B3451 is an unconjugated rabbit polyclonal antibody to HRD1 (SYVN1) (aa586-617) from human. It is reactive with human and mouse. Validated for IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
IF, IHC, IHC-P, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
KIAA1810 | Synoviolin | Synovial apoptosis inhibitor 1 | DER3 | HRD1 | SYVN1
Recommended Dilution: IF/ICC
1:200
Recommended Dilution: IHC-P
10 µg/ml
Recommended Dilution: WB
1:1000
UniProt Number
Q86TM6
SwissProt
Q86TM6

Target

Target
SYVN1 / HRD1
Antigen Species
Human
Specificity
This SYVN1 (HRD1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-617 amino acids from the C-terminal region of human SYVN1 (HRD1).
Epitope
This SYVN1 (HRD1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-617 amino acids from the C-terminal region of human SYVN1 (HRD1).
Gene Name
SYVN1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Volume
200 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions
Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
Recommended Storage Buffer
PBS

Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation. Kaneko M, Koike H, Saito R, Kitamura Y, Okuma Y, Nomura Y. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2010;30:3924-32.

PubMed: 20237263


Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR. The Journal of biological chemistry. 2011;286:41530-8.

PubMed: 21987572 · PMC: PMC3308864

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