LSBio
IHC-plus™ Polyclonal Rabbit anti-Human SREBF2 / SREBP2 Antibody (aa455-469, IHC, WB)

Nuclear Staining in Human Testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ Polyclonal Rabbit anti-Human SREBF2 / SREBP2 Antibody (aa455-469, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunocytochemistry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Bovine, Chicken, Dog, Hamster, Horse, Human, Mouse, Non-Human Primate, Pig, Rat
Format:Liquid
See all SREBF2 / SREBP2 antibodies →
$383.00each
Catalog Number: LS-B1609-1

For bulk orders or custom formulations:

Request a Quote

Overview

Description
SREBP2 antibody LS-B1609 is an unconjugated rabbit polyclonal antibody to SREBP2 (SREBF2) (aa455-469) from human. It is reactive with human, mouse, rat and other species. Validated for ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
ICC, IHC, IHC-P, WB
Reactivity
Bov, Can, Ck, Ham, Hr, Hu, Ms, NHP, Por, Rt
Predicted Reactivity
Mammal (Other), Xenopus
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
SREBP2 | SREBF2 | SREBP-2 | BHLHd2
Recommended Dilution: IF/ICC
1:150
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
1:200
UniProt Number
Q12772
SwissProt
Q12772

Target

Target
SREBF2 / SREBP2
Antigen Species
Human
Specificity
human SREBP-2 amino acids 455-469 (SPLLDDAKVKDEPDS)
Epitope
human SREBP-2 amino acids 455-469 (SPLLDDAKVKDEPDS)
Gene Name
SREBF2

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG
Origin Species
Human

Immunogen

Immunogen
Human SREBP-2 amino acids 455-469 (SPLLDDAKVKDEPDS). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Mouse, Rat, Dog, Bovine, Hamster, Elephant, Panda, Horse, Pig, Turkey, Chicken, Platypus, Lizard (100%); Bat, Xenopus (93%).

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.2, 0.02% Sodium Azide, 50% Glycerol
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store at -20°C.
Recommended Storage Buffer
PBS

Effect of cholesterol reduction on receptor signaling in neurons. Fukui K, Ferris HA, Kahn CR. The Journal of biological chemistry. 2015;290:26383-92.

PubMed: 26370080 · PMC: PMC4646295


Loss of astrocyte cholesterol synthesis disrupts neuronal function and alters whole-body metabolism. Ferris HA, Perry RJ, Moreira GV, Shulman GI, Horton JD, Kahn CR. Proceedings of the National Academy of Sciences of the United States of America. 2017 January;114:1189-1194.

PubMed: 28096339 · PMC: PMC5293102

Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at: technical@vectorlabs.com.