LSBio
IHC-plus™ Polyclonal Rabbit anti-Human SLC5A2 / SGLT2 Antibody (C-Terminus, IHC)

Anti-SLC5A2 antibody IHC of human kidney, collecting duct. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ Polyclonal Rabbit anti-Human SLC5A2 / SGLT2 Antibody (C-Terminus, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Horse, Human, Rat
Format:Liquid
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$449.00each
Catalog Number: LS-A2810-50

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Overview

Description
SGLT2 antibody LS-A2810 is an unconjugated rabbit polyclonal antibody to SGLT2 (SLC5A2) (C-Terminus) from human. It is reactive with human, rat and horse. Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
IHC, IHC-P
Reactivity
Hr, Hu, Rt
Predicted Reactivity
Bovine, Hamster, Mammal (Other), Mouse, Non-Human Primate
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Na(+)/glucose cotransporter 2 | SGLT2 | SLC5A2 | Sodium-glucose transporter 2 | Sodium/glucose cotransporter 2
Recommended Dilution: IHC-P
20 µg/ml
UniProt Number
P31639
SwissProt
P31639

Target

Target
SLC5A2 / SGLT2
Antigen Species
Human
Specificity
Human SLC5A2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Epitope
Human SLC5A2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Gene Name
SLC5A2

Antibody

Host Species
Rabbit
Clonality
Polyclonal

Immunogen

Immunogen
Synthetic 17 amino acid peptide from C-Terminus of human SLC5A2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Rat, Elephant, Horse (100%); Marmoset, Mouse, Hamster, Bat, Bovine (94%); Dog (88%); Panda, Rabbit (82%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.2, 0.09% Sodium Azide
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
No direct effect of SGLT2 activity on glucagon secretion. Rune E Kuhre, Seyed M Ghiasi, Alice E Adriaenssens, Nicolai J Wewer Albrechtsen, Daniel B Andersen, Alexander Aivazidis, Lihua Chen, Thomas Mandrup-Poulsen, Cathrine Ørskov, Fiona M Gribble, Frank Reimann, Nils Wierup, Björn Tyrberg, Jens J Holst. Diabetologia. 2019 Jun;62:1011-1023. PubMed: 30903205 PMC: PMC7212061

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