LSBio
IHC-plus™ Polyclonal Rabbit anti-Human IRS1 Antibody (IHC, IF, WB)

Anti-IRS1 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ Polyclonal Rabbit anti-Human IRS1 Antibody (IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
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$383.00each
Catalog Number: LS-B1373-0.05

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Overview

Description
IRS1 antibody LS-B1373 is an unconjugated rabbit polyclonal antibody to IRS1 from human. It is reactive with human and mouse. Validated for ELISA, ICC, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, ICC, IF, IHC, IHC-P, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
IRS-1 | HIRS-1 | Insulin receptor substrate 1 | IRS1
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
1 - 2 µg/ml
UniProt Number
P35568
SwissProt
P35568

Target

Target
IRS1
Antigen Species
Human
Gene Name
IRS1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A 16 AA synthetic peptide near the center of human IRS-1. The immunogen is located within aa 910-960 of IRS-1.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS containing 0.02% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS
The Medial Septum Is Insulin Resistant in the AD Presymptomatic Phase: Rescue by Nerve Growth Factor-Driven IRS1 Activation. Sposato V, Canu N, Fico E, Fusco S, Bolasco G, Ciotti MT, Spinelli M, Mercanti D, Grassi C, Triaca V, Calissano P. Molecular neurobiology. 2019 January;56:535-552. PubMed: 29736736 PMC: PMC6334735

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