LSBio
IHC-plus™ Polyclonal Rabbit anti-Human HPSE / Heparanase Antibody (IHC, WB)

Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ Polyclonal Rabbit anti-Human HPSE / Heparanase Antibody (IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
See all HPSE / Heparanase antibodies →
$658.00each
Catalog Number: LS-B2441-50

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Overview

Description
Heparanase antibody LS-B2441 is an unconjugated rabbit polyclonal antibody to Heparanase (HPSE) from human. It is reactive with human and mouse. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
IHC, IHC-P, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Endo-glucoronidase | Heparanase-1 | Heparanase | HPA | HSE1 | HEP | HPA1 | HPSE | HPSE1 | HPR1
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
1:2000
UniProt Number
Q9Y251
SwissProt
Q9Y251

Target

Target
HPSE / Heparanase
Antigen Species
Human
Specificity
Recognizes the 65kD precursor as well as the 50kD and 8kD subunits of human or mouse Heparanase.
Epitope
Recognizes the 65kD precursor as well as the 50kD and 8kD subunits of human or mouse Heparanase.
Gene Name
HPSE

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A heterodimeric recombinant protein consisting of the 50 kDa and 8 kDa subunits.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.2, 0.01% Thimerosal
Concentration
5.7 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: 4°C Long term: Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Inhibition of Heparanase in Pediatric Brain Tumor Cells Attenuates their Proliferation, Invasive Capacity, and In Vivo Tumor Growth. Spyrou A, Kundu S, Haseeb L, Yu D, Olofsson T, Dredge K, Hammond E, Barash U, Vlodavsky I, Forsberg-Nilsson K. Molecular cancer therapeutics. 2017 August;16:1705-1716. PubMed: 28716813

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