LSBio
IHC-plus™ Polyclonal Rabbit anti-Human Fractin Antibody (C-Terminus, IHC, IF, WB)

Anti-Fractin antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.

IHC-plus™ Polyclonal Rabbit anti-Human Fractin Antibody (C-Terminus, IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
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$495.00each
Catalog Number: LS-B6131-50

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Overview

Description
Fractin antibody LS-B6131 is an unconjugated rabbit polyclonal antibody to human Fractin (C-Terminus). Validated for ELISA, ICC, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, ICC, IF, IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Recommended Dilution: IF/ICC
1:400 - 1:1000
Recommended Dilution: IHC-P
1:100
Recommended Dilution: WB
1:1000 - 1:4000

Target

Target
Fractin
Antigen Species
Human
Specificity
By immunohistochemistry and Western blot, this antibody recognizes the 32kD Fractin fragment but not full-length beta actin.
Epitope
By immunohistochemistry and Western blot, this antibody recognizes the 32kD Fractin fragment but not full-length beta actin.

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Isotype
IgG

Immunogen

Immunogen
K-YELPD peptide representing the last five amino acids of the C-Terminus of 32kD Fractin fragment of beta-Actin. This sequence is absolutely conserved in Fractin fragments from human, mouse, rat, feline, porcine, ovine, bovine, canine, rabbit and guinea pig.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
Whole rabbit serum. No preservative added.
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
No
Purification Method
Unpurified (Serum / Ascites / Supernatant)

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A. Gaband[Character e9]-Rodr[Character ed]guez E, Boya P, Labrador V, Dotti CG, Ledesma MD. Cell death and differentiation. 2014 Jun;21:864-75. PubMed: 24488099 PMC: PMC4013520

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