LSBio
IHC-plus™ Polyclonal Rabbit anti-Human FANCD2 Antibody (N-Terminus, IHC)

Anti-FANCD2 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ Polyclonal Rabbit anti-Human FANCD2 Antibody (N-Terminus, IHC)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Dog, Human, Mouse, Non-Human Primate
Format:Liquid
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$383.00each
Catalog Number: LS-B493-0.05

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Overview

Description
FANCD2 antibody LS-B493 is an unconjugated rabbit polyclonal antibody to FANCD2 (N-Terminus) from human. It is reactive with human, mouse, dog and other species. Validated for IHC. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
IHC, IHC-P
Reactivity
Can, Hu, Ms, NHP
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
FA-D2 | FAD | FACD | FANCD2 | FA4 | FAD2 | FANCD | Protein FACD2
Recommended Dilution: IHC-P
2.5 - 5 µg/ml
UniProt Number
Q9BXW9
SwissProt
Q9BXW9

Target

Target
FANCD2
Antigen Species
Human
Specificity
FANCD2.
Epitope
FANCD2.
Gene Name
FANCD2

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Human FANCD2 fusion protein (N-Terminus fragment).
Immunogen Type
Fusion Protein (e.g., GST, MBP tag)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.05% Sodium Azide
Concentration
1 mg/mL
Volume
0.05 Milliliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance. Tuul M, Kitao H, Iimori M, Matsuoka K, Kiyonari S, Saeki H, Oki E, Morita M, Maehara Y. PloS one. 2013;8:e55361.

PubMed: 23383325 · PMC: PMC3562228


Significance of the Fanconi anemia FANCD2 protein in sporadic and metastatic human breast cancer. Rudland PS, Platt-Higgins AM, Davies LM, de Silva Rudland S, Wilson JB, Aladwani A, Winstanley JH, Barraclough DL, Barraclough R, West CR, Jones NJ. The American journal of pathology. 2010 Jun;176:2935-47.

PubMed: 20363922 · PMC: PMC2877854

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