LSBio
IHC-plus™ Polyclonal Rabbit anti-Human CYP17 / CYP17A1 Antibody (aa358-388, IHC, IF, WB)

Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ Polyclonal Rabbit anti-Human CYP17 / CYP17A1 Antibody (aa358-388, IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunocytochemistry, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
See all CYP17 / CYP17A1 antibodies →
$470.00each
Catalog Number: LS-B14227-200

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Overview

Description
CYP17A1 antibody LS-B14227 is an unconjugated rabbit polyclonal antibody to human CYP17A1 (CYP17) (aa358-388). Validated for ICC, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 4 publications.
Application
ICC, IF, IHC, IHC-P, WB
Reactivity
Hu
Predicted Reactivity
Non-Human Primate
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CYP17 | CYPXVII | CPT7 | CYP17A1 | Cytochrome P450-C17 | Cytochrome P450c17 | p450C17 | Steroid 17-alpha-monooxygenase | Cytochrome P450 17A1 | Cytochrome p450 XVIIA1 | S17AH
Recommended Dilution: IF/ICC
1:10 - 1:50
Recommended Dilution: IHC-P
1:100
Recommended Dilution: WB
1:1000
UniProt Number
P05093
SwissProt
P05093

Target

Target
CYP17 / CYP17A1
Antigen Species
Human
Specificity
This CYP17A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-388 amino acids from the Central region of human CYP17A1.
Epitope
This CYP17A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-388 amino acids from the Central region of human CYP17A1.
Gene Name
CYP17A1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.09% Sodium Azide
Concentration
2 mg/mL
Volume
200 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions
Maintain refrigerated at 2°C to 8°C for up to 6 months. For long term storage store at -20°C.
Recommended Storage Buffer
PBS

Identification of Somatic Mutations in CLCN2 in Aldosterone-Producing Adenomas. Juilee Rege, Kazutaka Nanba, Amy R Blinder, Samuel Plaska, Aaron M Udager, Pankaj Vats, Chandan Kumar-Sinha, Thomas J Giordano, William E Rainey, Tobias Else. Journal of the Endocrine Society. 2020 October;4:bvaa123.

PubMed: 33033789 · PMC: PMC7528565


Targeted Molecular Characterization of Aldosterone-Producing Adenomas in White Americans. Kazutaka Nanba, Kei Omata, Tobias Else, Peter C C Beck, Aya T Nanba, Adina F Turcu, Barbra S Miller, Thomas J Giordano, Scott A Tomlins, William E Rainey. The Journal of clinical endocrinology and metabolism. 2018 October;103:3869-3876.

PubMed: 30085035 · PMC: PMC6179168


Prevalence of Somatic Mutations in Aldosterone-Producing Adenomas in Japanese Patients. Kazutaka Nanba, Yuto Yamazaki, Nolan Bick, Kei Onodera, Yuta Tezuka, Kei Omata, Yoshikiyo Ono, Amy R Blinder, Scott A Tomlins, William E Rainey, Fumitoshi Satoh, Hironobu Sasano. The Journal of clinical endocrinology and metabolism. 2020 November;105:e4066-e4073.

PubMed: 32844168 · PMC: PMC7947976


Intratumoral steroid profiling of adrenal cortisol-producing adenomas by liquid chromatography- mass spectrometry. James P Teuber, Kazutaka Nanba, Adina F Turcu, Xuan Chen, Lili Zhao, Tobias Else, Richard J Auchus, William E Rainey, Juilee Rege. The Journal of steroid biochemistry and molecular biology. 2021 September;212:105924.

PubMed: 34089832 · PMC: PMC8734951

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