LSBio
IHC-plus™ Polyclonal Rabbit anti-Human CARD14 Antibody (aa291-340, IHC, IF)

Anti-CARD14 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.

IHC-plus™ Polyclonal Rabbit anti-Human CARD14 Antibody (aa291-340, IHC, IF)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Human, Mouse
Format:Liquid
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$383.00each
Catalog Number: LS-B11378-100

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Overview

Description
CARD14 antibody LS-B11378 is an unconjugated rabbit polyclonal antibody to CARD14 (aa291-340) from human. It is reactive with human and mouse. Validated for IF, IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IF, IHC, IHC-P
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
BIMP2 | Card-maguk protein 2 | Carma 2 | CARD14 | PrP | PSORS2 | PSS1 | CARMA2
Recommended Dilution: IF/ICC
1:100 - 1:500
Recommended Dilution: IHC-P
1:50
UniProt Number
Q9BXL6
SwissProt
Q9BXL6

Target

Target
CARD14
Antigen Species
Human
Specificity
CAR14 Antibody detects endogenous levels of total CAR14 protein.
Epitope
CAR14 Antibody detects endogenous levels of total CAR14 protein.
Gene Name
CARD14

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Synthetic peptide from human CAR14. (AA Range: 291-340)
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide, 50% Glycerol
Concentration
1 mg/mL
Volume
100 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at -20°C for up to 1 year.
Recommended Storage Buffer
PBS, 150 mM NaCl
Gain of function p.E138A alteration in Card14 leads to psoriasiform skin inflammation and implicates genetic modifiers in disease severity. John P Sundberg, C Herbert Pratt, Kathleen A Silva, Victoria E Kennedy, Wenning Qin, Timothy M Stearns, Jacqueline Frost, Beth A Sundberg, Anne M Bowcock. Experimental and molecular pathology. 2019 October;110:104286. PubMed: 31323190 PMC: PMC7318844

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