LSBio
IHC-plus™ Polyclonal Rabbit anti-Human ACVR1B / ALK4 Antibody (IHC, WB)

Anti-ACVR1 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ Polyclonal Rabbit anti-Human ACVR1B / ALK4 Antibody (IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
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$556.00each
Catalog Number: LS-B2695-0.05

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Overview

Description
ALK4 antibody LS-B2695 is an unconjugated rabbit polyclonal antibody to ALK4 (ACVR1B) from human. It is reactive with human and mouse. Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Hu, Ms
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ACTR-IB | ACTRIB | ALK4 | Activin receptor type IB | Activin A Receptor Type IB | Activin A receptor, type IB | Activin receptor-like kinase 4 | ACVR1B | ACVRLK4 | ALK-4 | Activin receptor type-1B | SKR2-2 | SKR2
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
1 µg/ml
UniProt Number
P36896
SwissProt
P36896

Target

Target
ACVR1B / ALK4
Antigen Species
Human
Specificity
At least three isoforms of ACVR1B are known to exist. This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1C.
Epitope
At least three isoforms of ACVR1B are known to exist. This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1C.
Gene Name
ACVR1B

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A 14 AA synthetic peptide near the C-Terminus of human ACVR1B. The immunogen is located within aa 140-190 of ACVR1B.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS containing 0.02% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS
The Dynamics of TGF-ß Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery. Miller DSJ, Bloxham RD, Jiang M, Gori I, Saunders RE, Das D, Chakravarty P, Howell M, Hill CS. Cell reports. 2018 November;25:1841-1855. PubMed: 30428352

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