LSBio
IHC-plus™ Polyclonal Goat anti-Human UCP2 Antibody (aa101-113, IHC, IF, WB)

Anti-UCP2 antibody IHC of human adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml.

IHC-plus™ Polyclonal Goat anti-Human UCP2 Antibody (aa101-113, IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Goat Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Bovine, Dog, Hamster, Horse, Human, Mammal (Other), Mouse, Non-Human Primate, Pig, Rabbit, Rat, Xenopus
Format:Liquid
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$495.00each
Catalog Number: LS-B3249-50

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Overview

Description
UCP2 antibody LS-B3249 is an unconjugated goat polyclonal antibody to UCP2 (aa101-113) from human. It is reactive with human, mouse, rat and other species. Validated for IF, IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 4 publications.
Application
ELISA, IF, IHC, IHC-P, WB
Reactivity
Bov, Can, Ham, Hr, Hu, Mml, Ms, NHP, Por, Rb, Rt, Xen
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
BMIQ4 | UCP 2 | Uncoupling protein 2 | UCP2 | UCPH | SLC25A8
Recommended Dilution: IF/ICC
10 µg/ml
Recommended Dilution: IHC-P
3.75 µg/ml
Recommended Dilution: WB
0.3 - 1 µg/ml
UniProt Number
P55851
SwissProt
P55851

Target

Target
UCP2
Antigen Species
Human
Specificity
Human UCP2.
Epitope
Human UCP2.
Gene Name
UCP2

Antibody

Host Species
Goat
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Peptide with sequence C-DSVKQFYTKGSEH, from the internal region of the protein sequence according to NP_003346.2.
Immunogen Type
Peptide

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
TBS

Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction. Fang EF, Scheibye-Knudsen M, Brace LE, Kassahun H, SenGupta T, Nilsen H, Mitchell JR, Croteau DL, Bohr VA. Cell. 2014 May;157:882-96.

PubMed: 24813611


AKI after conditional and kidney-specific knockdown of stanniocalcin-1. Huang L, Belousova T, Pan JS, Du J, Ju H, Lu L, Zhang P, Truong LD, Nuotio-Antar A, Sheikh-Hamad D. Journal of the American Society of Nephrology : JASN. 2014;25:2303-15.

PubMed: 24700878 · PMC: PMC4178431


Overexpression of stanniocalcin-1 inhibits reactive oxygen species and renal ischemia/reperfusion injury in mice. Huang L, Belousova T, Chen M, DiMattia G, Liu D, Sheikh-Hamad D. Kidney international. 2012;82:867-77.

PubMed: 22695329


Human stanniocalcin-1 suppresses angiotensin II-induced superoxide generation in cardiomyocytes through UCP3-mediated anti-oxidant pathway. Dajun Liu, Luping Huang, Yanlin Wang, Wei Wang, Xander H T Wehrens, Tatiana Belousova, Maen Abdelrahim, Gabriel DiMattia, David Sheikh-Hamad. PloS one. 2012 June;7:e36994.

PubMed: 22693564 · PMC: PMC3365029

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