LSBio
IHC-plus™ Polyclonal Goat anti-Human CDKN1B / p27 Kip1 Antibody (aa153-165, IHC, WB)

Anti-CDKN1B / p27 Kip1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ Polyclonal Goat anti-Human CDKN1B / p27 Kip1 Antibody (aa153-165, IHC, WB)

Primary AntibodyLSBio Guarantee
Antibody:Goat Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
See all CDKN1B / p27 Kip1 antibodies →
$495.00each
Catalog Number: LS-B3943-50

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Overview

Description
P27 Kip1 antibody LS-B3943 is an unconjugated goat polyclonal antibody to human p27 Kip1 (CDKN1B) (aa153-165). Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
CDKN1B | KIP1 | MEN1B | P27 Kip1 | p27KIP1 | MEN4 | CDKN4
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
0.1 - 0.3 µg/ml
UniProt Number
P46527
SwissProt
P46527

Target

Target
CDKN1B / p27 Kip1
Antigen Species
Human
Specificity
Human CDKN1B / p27 Kip1.
Epitope
Human CDKN1B / p27 Kip1.
Gene Name
CDKN1B

Antibody

Host Species
Goat
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
Peptide with sequence C-KRPATDDSSTQNK, from the internal region of the protein sequence according to NP_004055.1.
Immunogen Type
Peptide

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
No
Preservative
Yes
Purification Method
Ammonium Sulfate Precipitation

Storage & Handling

Storage Conditions
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
TBS
A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-ß2 signaling. Chandrani Mondal, Majo J Gacha-Garay, Kathryn A Larkin, Rebecca C Adikes, Julie S Di Martino, Chen-Chi Chien, Madison Fraser, Ireti Eni-Aganga, Esperanza Agullo-Pascual, Katarzyna Cialowicz, Umut Ozbek, Alexandra Naba, Angelo Gaitas, Tian-Ming Fu, Srigokul Upadhyayula, Eric Betzig, David Q Matus, Benjamin L Martin, Jose Javier Bravo-Cordero. Cell reports. 2022 September;40:111358. PubMed: 36130489 PMC: PMC9596226

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