PDGF-BB Antibody
Catalog Number: LS-C104675
2 sizes / from $364.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Western Blot
Reactivity: Human
Format: Lyophilized
Anti-PDGFB antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
IHC-plus™ PDGF-BB Antibody (aa222-233)
Primary AntibodyLSBio Guarantee
| Antibody: | Goat Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin |
| Reactivity: | Bovine, Human, Sheep |
| Format: | Liquid |
$495.00each
Catalog Number: LS-B4182-50
Catalog Number: LS-B4182
For bulk orders or custom formulations:
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- Description
- PDGF-BB antibody LS-B4182 is an unconjugated goat polyclonal antibody to PDGF-BB (aa222-233) from human. It is reactive with human, bovine and sheep. Validated for IF, IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
- Application
- ELISA, IF, IHC, IHC-P
- Reactivity
- Bov, Hu, Sh
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- PDGF-BB | PDGF-b | PDGFB | SSV | PDGF subunit B | PDGF-2 | PDGF2 | Proto-oncogene c-Sis | SIS | C-sis | PDGF, B chain
- Recommended Dilution: IF/ICC
- 10 µg/ml
- Recommended Dilution: IHC-P
- 3.75 µg/ml
- UniProt Number
- P01127
- NCBI GenBank
- NM_002608 | NP_002599.1
- SwissProt
- P01127
Target
- Target
- PDGF-BB
- Antigen Species
- Human
- Specificity
- Human PDGFB.
- Epitope
- Human PDGFB.
- Gene Name
- PDGFB
Antibody
- Host Species
- Goat
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- Peptide with sequence C-KHRKFKHTHDKT, from the C-Terminus of protein sequence according to NP_002599.1NP_148937.1.
- Immunogen Type
- Peptide
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
- Concentration
- 0.5 mg/mL
- Animal Free
- No
- Carrier-Free
- No
- Preservative
- Yes
- Purification Method
- Ammonium Sulfate Precipitation
Storage & Handling
- Storage Conditions
- Aliquot and store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- TBS
Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G alpha q-mediated Rho and alpha v beta 6 integrin-dependent activation of TGF- beta . Geng H, Lan R, Singha PK, Gilchrist A, Weinreb PH, Violette SM, Weinberg JM, Saikumar P, Venkatachalam MA. The American journal of pathology. 2012 Oct;181:1236-49.
PubMed: 22885106 · PMC: PMC3463629
Creation of disease-inspired biomaterial environments to mimic pathological events in early calcific aortic valve disease. Ana M Porras, Jennifer A Westlund, Austin D Evans, Kristyn S Masters. Proceedings of the National Academy of Sciences of the United States of America. 2018 January;115:E363-E371.
PubMed: 29282325 · PMC: PMC5776956
