LSBio
IHC-plus™ NPC1L1 Antibody (aa500-600)

Anti-NPC1L1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ NPC1L1 Antibody (aa500-600)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
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$383.00each
Catalog Number: LS-B506-0.1

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Overview

Description
NPC1L1 antibody LS-B506 is an unconjugated rabbit polyclonal antibody to NPC1L1 (aa500-600) from rat. It is reactive with human, mouse and rat. Validated for IHC and WB. Cited in 1 publication.
Application
IHC, IHC-P, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Niemann-Pick C1-like protein 1 | NPC1L1 | NPC11L1 | NPC1-like 1
Recommended Dilution: IHC-P
10 - 20 µg/ml
Recommended Dilution: WB
1:500
UniProt Number
Q9UHC9
SwissProt
Q9UHC9

Target

Target
NPC1L1
Antigen Species
Rat
Specificity
NPC1L1 protein.
Epitope
NPC1L1 protein.
Gene Name
NPC1L1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A synthetic peptide made to an internal region of rat NPC1L1(between residues 500-600)
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.02% Sodium Azide
Concentration
1 mg/mL
Volume
0.1 Milliliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Transgenic mice lacking FGF15/19-SHP phosphorylation display altered bile acids and gut bacteria, promoting nonalcoholic fatty liver disease. Young-Chae Kim, Ming Qi, Xingchen Dong, Sunmi Seok, Hao Sun, Byron Kemper, Ting Fu, Jongsook Kim Kemper. The Journal of biological chemistry. 2023 August;299:104946. PubMed: 37348559 PMC: PMC10394163

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