LSBio
IHC-plus™ NFKB1 / NF-Kappa-B Antibody (clone 4D1)

Anti-NFKB1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.

IHC-plus™ NFKB1 / NF-Kappa-B Antibody (clone 4D1)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human
Format:Liquid
See all NFKB1 / NF-Kappa-B antibodies →
$383.00each
Catalog Number: LS-B1668-50

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Overview

Description
NF-Kappa-B antibody LS-B1668 is an unconjugated mouse monoclonal antibody to human NF-Kappa-B (NFKB1). Validated for IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 4 publications.
Application
IF, IHC, IHC-P, WB
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Ebp- 1 | EBP-1 | NF-KappaB p50 | NFkappaB | NFKB-p50 | KBF1 | NF-kappa-B | NF-kappaB | NF-kB1 | NFKB-p105 | p105 | p50 | DNA binding factor KBF1 | DNA-binding factor KBF1 | NF-kappabeta | NFKB1
Recommended Dilution: IHC-P
15 µg/ml
UniProt Number
P19838
SwissProt
P19838

Target

Target
NFKB1 / NF-Kappa-B
Antigen Species
Human
Specificity
Recombinant full-length human NF-kB p50
Epitope
Recombinant full-length human NF-kB p50
Gene Name
NFKB1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
4D1

Immunogen

Immunogen
Recombinant human NFKB1.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
Phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C. Avoid freezing.
Recommended Storage Buffer
Phosphate-buffered

Requirement for both JAK-mediated PI3K signaling and ACT1/TRAF6/TAK1-dependent NF-kappaB activation by IL-17A in enhancing cytokine expression in human airway epithelial cells. Huang F, Kao CY, Wachi S, Thai P, Ryu J, Wu R. Journal of immunology (Baltimore, Md. : 1950). 2007;179:6504-13.

PubMed: 17982039


Requirements for two proximal NF-kappaB binding sites and IkappaB-zeta in IL-17A-induced human beta-defensin 2 expression by conducting airway epithelium. Kao CY, Kim C, Huang F, Wu R. The Journal of biological chemistry. 2008;283:15309-18.

PubMed: 18362142 · PMC: PMC2397472


NF-B regulates MICA gene transcription in endothelial cell through a genetically inhibitable control site. Lin D, Lavender H, Soilleux EJ, O'Callaghan CA. The Journal of biological chemistry. 2012;287:4299-310.

PubMed: 22170063 · PMC: PMC3281736


1,25-dihydroxyvitamin D3 impairs NF- kappa B activation in human naïve B cells. Geldmeyer-Hilt K, Heine G, Hartmann B, Baumgrass R, Radbruch A, Worm M. Biochemical and biophysical research communications. 2011 Apr;407:699-702.

PubMed: 21420936

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