LSBio
IHC-plus™ Neurofibromin / NF1 Antibody (aa2760-C-term)

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ Neurofibromin / NF1 Antibody (aa2760-C-term)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Human, Mouse
Format:Liquid
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$470.00each
Catalog Number: LS-B14758-50

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Overview

Description
NF1 antibody LS-B14758 is an unconjugated rabbit polyclonal antibody to NF1 (Neurofibromin) (aa2760-C-term) from human. It is reactive with human and mouse. Validated for IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
IHC, IHC-P, IP, WB
Reactivity
Hu, Ms
Predicted Reactivity
Rat
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
VRNF | Neurofibromin 1 | NFNS | WSS | Neurofibromin | NF1
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: IP
2 - 10 µg/mg lysate
Recommended Dilution: WB
1:1000 - 1:10000
UniProt Number
P21359
NCBI GenBank
NM_000267 | NP_000258.1
SwissProt
P21359

Target

Target
Neurofibromin / NF1
Antigen Species
Human
Epitope
Region between residue 2760 and the C-terminus (residue 2818) of human Neurofibromin 1 using the numbering given in entry NP_000258.1 (GeneID 4763).
Gene Name
NF1

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A portion of GeneID: 4763 corresponding to amino acids between 2760 and the C-Terminus of UniprotID: P21359

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
Tris-citrate/phosphate buffer, pH 7-8, 0.09% sodium azide.
Concentration
1 mg/mL
Volume
50 Microliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 2-8°C for up to one year.
Recommended Storage Buffer
Tris-citrate
Expression of neurofibromin 1 in colorectal cancer and cetuximab resistance. Eunyoung Tak, Minhee Kim, Youngra Cho, Sueun Choi, Jihun Kim, Buhm Han, Hyung-Don Kim, Chloe Soo-Hyun Jang, Jeong Eun Kim, Yong Sang Hong, Sun Young Kim, Tae Won Kim. Oncology reports. 2022 Jan;;47:15. PubMed: 34779495 PMC: PMC8611403
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