LSBio
IHC-plus™ NAK / TBK1 Antibody (aa563-577, clone 108A429)

Anti-TBK1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ NAK / TBK1 Antibody (aa563-577, clone 108A429)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Bovine, Dog, Hamster, Horse, Human, Mouse, Non-Human Primate, Pig, Rabbit, Rat
Format:Liquid
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$383.00each
Catalog Number: LS-B1317-50

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Overview

Description
TBK1 antibody LS-B1317 is an unconjugated mouse monoclonal antibody to TBK1 (NAK) (aa563-577) from human. It is reactive with human, mouse, rat and other species. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
IHC, IHC-P, WB
Reactivity
Bov, Can, Ham, Hr, Hu, Ms, NHP, Por, Rb, Rt
Predicted Reactivity
Chicken
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
nak | T2K | TBK1 | NAK | NF-kappa-B-activating kinase | NF-kB-activating kinase | TANK-binding kinase 1
Recommended Dilution: IHC-P
10 µg/ml
Recommended Dilution: WB
1 - 2 µg/ml
UniProt Number
Q9UHD2
SwissProt
Q9UHD2

Target

Target
NAK / TBK1
Antigen Species
Human
Specificity
A synthetic peptide corresponding to amino acids 563-577 YYQFKKDKAERRLAYC of human TBK1. GenBank no. NP-037386.1 was used as immunogen. This sequence is 100% conserved between human, mouse, rat, dog and cow.
Epitope
A synthetic peptide corresponding to amino acids 563-577 YYQFKKDKAERRLAYC of human TBK1. GenBank no. NP-037386.1 was used as immunogen. This sequence is 100% conserved between human, mouse, rat, dog and cow.
Gene Name
TBK1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
108A429
Light Chain
Kappa Light Chain
Origin Species
Human

Immunogen

Immunogen
A synthetic peptide corresponding to amino acids 563-577 (YYQFKKDKAERRLAYC) of human TBK1 was used as immunogen for this antibody. This sequence is 100% conserved between human, mouse, rat, dog and cow. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Hamster, Panda, Horse, Rabbit, Pig (100%); Elephant, Chicken, Platypus (93%); Bat, Turkey, Lizard (87%); Xenopus, Pufferfish, Zebrafish, Stickleback (80%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, 0.05% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Whole-genome sequencing reveals important role for TBK1 and OPTN mutations in frontotemporal lobar degeneration without motor neuron disease. Pottier C, Bieniek KF, Finch N, van de Vorst M, Baker M, Perkersen R, Brown P, Ravenscroft T, van Blitterswijk M, Nicholson AM, DeTure M, Knopman DS, Josephs KA, Parisi JE, Petersen RC, Boylan KB, Boeve BF, Graff-Radford NR, Veltman JA, Gilissen C, Murray ME, Dickson DW, Rademakers R. Acta neuropathologica. 2015;130:77-92. PubMed: 25943890 PMC: PMC4470809

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