Monoclonal Mouse Biotin Antibody
Catalog Number: LS-C127042-200
200 µg / $755.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Format: Liquid
Anti-IL-17 antibody IHC of mouse spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
IHC-plus™ Monoclonal Rat anti-Mouse IL17 Antibody (clone TC11-18H10, IHC, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Rat Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Mouse |
| Format: | Liquid |
$505.00each
Catalog Number: LS-B4912-0.1
Catalog Number: LS-B4912
For bulk orders or custom formulations:
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- Description
- IL17 antibody LS-B4912 is an unconjugated rat monoclonal antibody to mouse IL17. Validated for ELISA, Flow, IHC and WB. Cited in 2 publications.
- Application
- ELISA, FC, IHC, IHC-P, WB
- Reactivity
- Ms
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Recommended Dilution: IHC-P
- 10 µg/ml
Target
- Target
- IL17
- Antigen Species
- Mouse
- Specificity
- Recognizes mouse Interleukin 17, a 32kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217).
- Epitope
- Recognizes mouse Interleukin 17, a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.
Antibody
- Host Species
- Rat
- Clonality
- Monoclonal
- Clone
- TC11-18H10
Immunogen
- Immunogen
- E. coli-expressed, recombinant mouse IL-17A
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- BBS
- Concentration
- 0.5 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Purification Method
- Other
Storage & Handling
- Storage Conditions
- Store at -20°C. Avoid freeze-thaw cycles. Store undiluted.
- Recommended Storage Buffer
- bbs
Role of IL-17A in Chronic Rhinosinusitis With Nasal Polyp. Gwanghui Ryu , Jun Sang Bae , Ji Hye Kim, Eun Hee Kim, Lele Lyu, Young Jun Chung, Ji Hun Mo. Allergy, asthma & immunology research. 2020 May;12:507-522.
PubMed: 32141263 · PMC: PMC7061155
Particulate Matter Exposure Aggravates IL-17-Induced Eye and Nose Inflammation in an OVA/Poly(I:C) Mouse Model. Jun-Sang Bae , Soo Bin Oh , Jeongyun Kim, Hoon Kim, Ji Hye Kim, Eun-Hee Kim, Kyong Jin Cho, Ji-Hun Mo. Allergy, asthma & immunology research. 2022 January;14:59-72.
PubMed: 34983107 · PMC: PMC8724832