Monoclonal Mouse Biotin Antibody
Catalog Number: LS-C127042-200
200 µg / $755.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Format: Liquid
Anti-PABPN1 / PABP2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50-1:100.
IHC-plus™ Monoclonal Rabbit anti-Human PABPN1 / PABP2 Antibody (clone EP3001Y, Internal, IHC, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Monoclonal |
| Applications: | Flow Cytometry, Immunocytochemistry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse |
| Format: | Liquid |
$383.00each
Catalog Number: LS-B8482-50
Catalog Number: LS-B8482
For bulk orders or custom formulations:
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- Description
- PABP2 antibody LS-B8482 is an unconjugated rabbit monoclonal antibody to PABP2 (PABPN1) (Internal) from human. It is reactive with human and mouse. Validated for Flow, ICC, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
- Application
- FC, ICC, IHC, IHC-P, WB
- Reactivity
- Hu, Ms
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- PABP2 | PABPN1 | Poly(A)-binding protein 2 | OPMD | PABII | PABP-2 | Poly(A) binding protein 2 | Poly(A) binding protein II | Poly(A)-binding protein II | PAB2
- Recommended Dilution: FC
- 1:60
- Recommended Dilution: IF/ICC
- 1:100 - 1:250
- Recommended Dilution: IHC-P
- 1:50 - 1:100
- Recommended Dilution: WB
- 1:10000 - 1:50000
- UniProt Number
- Q86U42
- NCBI GenBank
- NM_004643 | NP_004634.1
- SwissProt
- Q86U42
Target
- Target
- PABPN1 / PABP2
- Antigen Species
- Human
- Gene Name
- PABPN1
Antibody
- Host Species
- Rabbit
- Clonality
- Monoclonal
- Clone
- EP3001Y
- Origin Species
- Human
Immunogen
- Immunogen
- A synthetic peptide corresponding to residues in human PABP2.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- Tris-Glycine-NaCl or PBS, pH 7.2-7.4, 40-50% Glycerol, 0.01% sodium azide, 0.05% BSA
- Volume
- 50 Microliter
- Animal Free
- No
- Carrier-Free
- No
- Preservative
- Yes
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
- Recommended Storage Buffer
- Tris-Glycine, NaCl, PBS
PABPN1-Dependent mRNA Processing Induces Muscle Wasting. Riaz M, Raz Y, van Putten M, Paniagua-Soriano G, Krom YD, Florea BI, Raz V. PLoS genetics. 2016;12:e1006031.
PubMed: 27152426 · PMC: PMC4859507
Dysfunctional transcripts are formed by alternative polyadenylation in OPMD. Raz V, Dickson G, 't Hoen PAC. Oncotarget. 2017;8:73516-73528.
PubMed: 29088723
Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability. Cyriel Sebastiaan Olie, Erik van der Wal, Domagoj Cikes, Loes Maton, Jessica C de Greef, I-Hsuan Lin, Yi-Fan Chen, Elsayad Kareem, Josef M Penninger, Benedikt M Kessler, Vered Raz. Scientific reports. 2020 October;10:17621.
PubMed: 33077830 · PMC: PMC7572364