Monoclonal Mouse Biotin Antibody
Catalog Number: LS-C127042-200
200 µg / $755.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Format: Liquid
Anti-Myosin, Cardiac Heavy Chain antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
IHC-plus™ Monoclonal Mouse anti-Human Myosin, Cardiac Heavy Chain Antibody (IHC, IF, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Frozen, Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Bovine, Dog, Human, Mouse, Pig, Rabbit, Rat |
| Format: | Liquid |
$495.00each
Catalog Number: LS-B6307-50
Catalog Number: LS-B6307
For bulk orders or custom formulations:
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- Description
- Myosin, Cardiac Heavy Chain antibody LS-B6307 is an unconjugated mouse monoclonal antibody to Myosin, Cardiac Heavy Chain from human. It is reactive with human, mouse, rat and other species. Validated for ELISA, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
- Application
- ELISA, IF, IHC, IHC-F, IHC-P, WB
- Reactivity
- Bov, Can, Hu, Ms, Por, Rb, Rt
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Recommended Dilution: IHC-F
- 10 µg/ml
- Recommended Dilution: IHC-P
- 5 µg/ml
Target
- Target
- Myosin, Cardiac Heavy Chain
- Antigen Species
- Human
- Specificity
- This antibody is myosin alpha and beta heavy chain specific. Affinity constants for: Human ventricular myosin heavy chains - 3.33 x 10x8/M Human atrial myosin heavy chains - 1.48 x 10x8 /M Human skeletal muscle myosin - 1.06 x 10x8/M Canine cardiac myosin heavy chains - 2.06 x 10x8/M. 3-48 antibody cross-reacts with heavy chains of human myosin isolated from: slow skeletal muscle, fast skeletal muscle, eye muscle, and streptococcal M5 peptide. It does not react with human platelet, smooth muscle myosin heavy chains, myosin light chains, myosin fragments circulating in blood of patients with myocardial infarction, nor does it react with any other human tissue antigens or blood cells. Myosin heavy chain is specific for cardiomyocytes. Species cross-reactivity: Cross-reacts with bovine, Human, Mouse, Rabbit, Rat, canine and porcine.
- Epitope
- This antibody is myosin alpha and beta heavy chain specific. Affinity constants for: Human ventricular myosin heavy chains - 3.33 x 10x8/M Human atrial myosin heavy chains - 1.48 x 10x8 /M Human skeletal muscle myosin - 1.06 x 10x8/M Canine cardiac myosin heavy chains - 2.06 x 10x8/M. 3-48 antibody cross-reacts with heavy chains of human myosin isolated from: slow skeletal muscle, fast skeletal muscle, eye muscle, and streptococcal M5 peptide. It does not react with human platelet, smooth muscle myosin heavy chains, myosin light chains, myosin fragments circulating in blood of patients with myocardial infarction, nor does it react with any other human tissue antigens or blood cells. Myosin heavy chain is specific for cardiomyocytes. Species cross-reactivity: Cross-reacts with bovine, Human, Mouse, Rabbit, Rat, canine and porcine.
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Light Chain
- Kappa Light Chain
Immunogen
- Immunogen
- Full length native protein (purified) (Human).
- Immunogen Type
- Native Protein (Purified from Natural Source)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- No preservatives added
- Concentration
- 1 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- No
- Purification Method
- Other
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Repression of Osmr and Fgfr1 by miR-1/133a prevents cardiomyocyte dedifferentiation and cell cycle entry in the adult heart. Melissa Valussi, Johannes Besser, Katharina Wystub-Lis, Sven Zukunft, Manfred Richter, Thomas Kubin, Thomas Boettger, Thomas Braun. Science advances. 2021 Oct;7:eabi6648. PubMed: 34644107 PMC: PMC8514096