Monoclonal Mouse Biotin Antibody
Catalog Number: LS-C127042-200
200 µg / $755.00
Antibody: Mouse Monoclonal
Applications: Enzyme-Linked Immunosorbent Assay
Format: Liquid
Anti-MDM4 / MDMX antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
IHC-plus™ Monoclonal Mouse anti-Human MDM4 / MDMX Antibody (clone 2D10F4, aa 2-185, IHC, IF, WB)
Primary AntibodyLSBio Guarantee
| Antibody: | Mouse Monoclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human |
| Format: | Liquid |
$383.00each
Catalog Number: LS-B4097-50
Catalog Number: LS-B4097
For bulk orders or custom formulations:
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- Description
- MDMX antibody LS-B4097 is an unconjugated mouse monoclonal antibody to human MDMX (MDM4) (aa 2-185). Validated for ELISA, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
- Application
- ELISA, IF, IHC, IHC-P, WB
- Reactivity
- Hu
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Monoclonal Antibodies
- Alternative Names
- Mdm2-like p53-binding protein | MDM4 | MDMX | HDMX | MRP1 | p53-binding protein Mdm4 | Protein Mdm4 | Double minute 4 protein | MDM4-related protein 1 | Protein Mdmx
- Recommended Dilution: ELISA
- 1:10000
- Recommended Dilution: IF/ICC
- 1:200 - 1:1000
- Recommended Dilution: IHC-P
- 1:200
- Recommended Dilution: WB
- 1:100 - 1:500
- UniProt Number
- O15151
- NCBI GenBank
- NM_002393 | NP_002384.2
- SwissProt
- O15151
Target
- Target
- MDM4 / MDMX
- Antigen Species
- Human
- Specificity
- Human
- Epitope
- Human
- Gene Name
- MDM4
Antibody
- Host Species
- Mouse
- Clonality
- Monoclonal
- Clone
- 2D10F4
- Isotype
- IgG1
- Origin Species
- Human
Immunogen
- Immunogen
- Purified recombinant fragment of human MDM4 expressed in E. Coli.
- Immunogen Type
- Recombinant Protein Fragment
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- Ascitic fluid, 0.03% sodium azide
- Volume
- 50 Microliter
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Unpurified (Serum / Ascites / Supernatant)
Storage & Handling
- Storage Conditions
- Short term: store at 4°C. Long term: store at -20°C.
Inhibition of MDM2 homodimerization by XIAP IRES stabilizes MDM2, influencing cancer cell survival. Liu T, Zhang H, Xiong J, Yi S, Gu L, Zhou M. Molecular cancer. 2015;14:65.
PubMed: 25888903 · PMC: PMC4379586
FKBP12 enhances sensitivity to chemotherapy-induced cancer cell apoptosis by inhibiting MDM2. Liu T, Xiong J, Yi S, Zhang H, Zhou S, Gu L, Zhou M. Oncogene. 2017;36:1678-1686.
PubMed: 27617579