LSBio
IHC-plus™ Monoclonal Mouse anti-Human Gasdermin D / GSDMD Antibody (clone 3F12-1B2, IHC, IF)

Anti-GSDMD / DFNA5L antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ Monoclonal Mouse anti-Human Gasdermin D / GSDMD Antibody (clone 3F12-1B2, IHC, IF)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin
Reactivity:Human
Format:Liquid
See all Gasdermin D / GSDMD antibodies →
$470.00each
Catalog Number: LS-B4537-50

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Overview

Description
GSDMD antibody LS-B4537 is an unconjugated mouse monoclonal antibody to human GSDMD (Gasdermin D). Validated for ELISA, IF and IHC. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IF, IHC, IHC-P
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
DF5L | Gasdermin domain containing 1 | FKSG10 | Gasdermin D | DFNA5L | Gasdermin-D | GSDMD | GSDMDC1
Recommended Dilution: IF/ICC
10 µg/ml
Recommended Dilution: IHC-P
5 µg/ml
UniProt Number
P57764
SwissProt
P57764

Target

Target
Gasdermin D / GSDMD
Antigen Species
Human
Gene Name
GSDMD

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
3F12-1B2
Light Chain
Kappa Light Chain
Origin Species
Human

Immunogen

Immunogen
GSDMDC1 (AAH08904, 1 aa ~ 485 aa) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen Type
Full-Length Recombinant Protein

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4
Concentration
0.5 mg/mL
Animal Free
No
Carrier-Free
Yes
Purification Method
Protein A Affinity

Storage & Handling

Storage Conditions
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
Novel Majeed Syndrome-Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis. Farzana Bhuyan, Adriana A de Jesus, Jacob Mitchell, Evgenia Leikina, Rachel VanTries, Ronit Herzog, Karen B Onel, Andrew Oler, Gina A Montealegre Sanchez, Kim A Johnson, Lena Bichell, Bernadette Marrero, Luis Fernandez De Castro, Yan Huang, Katherine R Calvo, Michael T Collins, Sundar Ganesan, Leonid V Chernomordik, Polly J Ferguson, Raphaela Goldbach-Mansky. Arthritis & rheumatology. 2021 Jun;;73:1021-1032. PubMed: 33314777 PMC: PMC8252456

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