LSBio
IHC-plus™ Monoclonal Mouse anti-Human FBN1 / Fibrillin 1 Antibody (clone 26, aa45-450, IHC, IF, WB)

Anti-FBN1 / Fibrillin 1 antibody IHC of human prostate, extra cellular matrix. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ Monoclonal Mouse anti-Human FBN1 / Fibrillin 1 Antibody (clone 26, aa45-450, IHC, IF, WB)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Immunoprecipitation, Western Blot
Reactivity:Bovine, Chicken, Human
Format:Liquid
See all FBN1 / Fibrillin 1 antibodies →
$495.00each
Catalog Number: LS-B5512-50

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Overview

Description
Fibrillin 1 antibody LS-B5512 is an unconjugated mouse monoclonal antibody to Fibrillin 1 (FBN1) (aa45-450) from human. It is reactive with human, bovine and chicken. Validated for ELISA, IF, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
ELISA, IF, IHC, IHC-P, IP, WB
Reactivity
Bov, Ck, Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
ACMICD | FBN1 | Fibrillin 1 | Fibrillin-1 | FBN | ECTOL1 | GPHYSD2 | MASS | MFS1 | OCTD | SSKS | WMS2 | Fibrillin 1 (Marfan syndrome) | Fibrillin 15 | SGS | WMS
Recommended Dilution: IHC-P
10 µg/ml
NCBI GenBank
NM_000138

Target

Target
FBN1 / Fibrillin 1
Antigen Species
Human
Specificity
Recognizes human Fibrillin-1. Epitope mapping studies identify the binding site of this antibody to amino terminal end of the molecule, between amino acid residues 45 and 450. Species cross-reactivity: Human, chicken and bovine.
Epitope
Recognizes human Fibrillin-1. Epitope mapping studies identify the binding site of this antibody to amino terminal end of the molecule, between amino acid residues 45 and 450. Species cross-reactivity: Human, chicken and bovine.

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
26

Immunogen

Immunogen
Human Fibrillin-1

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.6, 0.09% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Other

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Defining the Extracellular Matrix of Rhabdomyosarcoma. Xiaolei Lian, J Steffan Bond, Narendra Bharathy, Sergei P Boudko, Elena Pokidysheva, Jack F Shern, Melvin Lathara, Takako Sasaki, Teagan Settelmeyer, Megan M Cleary, Ayeza Bajwa, Ganapati Srinivasa, Christopher P Hartley, Hans Peter Bächinger, Atiya Mansoor, Sakir H Gultekin, Noah E Berlow, Charles Keller. Frontiers in oncology. 2021 March;11:601957.

PubMed: 33708626 · PMC: PMC7942227


FBXO2 Promotes Proliferation of Endometrial Cancer by Ubiquitin-Mediated Degradation of FBN1 in the Regulation of the Cell Cycle and the Autophagy Pathway. Xiaoxia Che, Fangfang Jian, Ying Wang, Jingjing Zhang, Jian Shen, Qi Cheng, Xi Wang, Nan Jia, Weiwei Feng. Frontiers in cell and developmental biology. 2020 September;8:843.

PubMed: 32984335 · PMC: PMC7487413

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