MANF / ARMET Antibody
Catalog Number: LS-C406140
4 sizes / from $260.00
Antibody: Rabbit Polyclonal
Applications: Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general)
Reactivity: Human, Mouse, Rat
Format: Liquid
Anti-MANF / ARMET antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
IHC-plus™ MANF / ARMET Antibody
Primary AntibodyLSBio Guarantee
| Antibody: | Rabbit Polyclonal |
| Applications: | Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot |
| Reactivity: | Human, Mouse, Rat |
| Format: | Liquid |
$556.00each
Catalog Number: LS-B2688-0.05
Catalog Number: LS-B2688
For bulk orders or custom formulations:
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- Description
- ARMET antibody LS-B2688 is an unconjugated rabbit polyclonal antibody to ARMET (MANF) from human. It is reactive with human, mouse and rat. Validated for ELISA, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 5 publications.
- Application
- ELISA, IF, IHC, IHC-P, WB
- Reactivity
- Hu, Ms, Rt
- Intended Use
- Research Use Only
- Guarantees
- This product carries the LSBio 100% Guarantee. ✓
- Category
- Antibodies > Primary Antibodies > Polyclonal Antibodies
- Alternative Names
- ARP | ARMET | MANF | Arginine-rich protein | Protein ARMET
- Recommended Dilution: IHC-P
- 5 µg/ml
- Recommended Dilution: WB
- 1 - 2 µg/ml
- UniProt Number
- P55145
- NCBI GenBank
- NM_006010 | NP_006001.4
- SwissProt
- P55145
Target
- Target
- MANF / ARMET
- Antigen Species
- Human
- Specificity
- This antibody does not cross-react with CDNF.
- Epitope
- This antibody does not cross-react with CDNF.
- Gene Name
- MANF
Antibody
- Host Species
- Rabbit
- Clonality
- Polyclonal
- Origin Species
- Human
Immunogen
- Immunogen
- A 12 AA synthetic peptide near the C-Terminus of human MANF. The immunogen is located within the last 50 AA of MANF.
- Immunogen Type
- Synthetic Peptide (Linear)
Format
- Conjugate/Label
- Unconjugated
- Format
- Liquid
- Formulation
- PBS containing 0.02% Sodium Azide
- Concentration
- 1 mg/mL
- Animal Free
- No
- Carrier-Free
- Yes
- Preservative
- Yes
- Purification Method
- Affinity Purified
Storage & Handling
- Storage Conditions
- Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
- Recommended Storage Buffer
- PBS
Piperine ameliorates SCA17 neuropathology by reducing ER stress. Guo J, Cui Y, Liu Q, Yang Y, Li Y, Weng L, Tang B, Jin P, Li XJ, Yang S, Li S. Molecular neurodegeneration. 2018 January;13:4.
PubMed: 29378605 · PMC: PMC5789626
Mesencephalic Astrocyte-Derived Neurotrophic Factor Is Upregulated with Therapeutic Fasting in Humans and Diet Fat Withdrawal in Obese Mice. Galli E, Rossi J, Neumann T, Andressoo JO, Drinda S, Lindholm P. Science advances. 2019 October;9:14318.
PubMed: 31586115 · PMC: PMC6778185
Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Is Highly Expressed in Mouse Tissues With Metabolic Function. Danilova T, Galli E, Pakarinen E, Palm E, Lindholm P, Saarma M, Lindahl M. Frontiers in endocrinology. 2019 November;10.
PubMed: 31781038 · PMC: PMC6851024
MANF Is Neuroprotective in Early Stages of EAE, and Elevated in Spinal White Matter by Treatment With Dexamethasone. Jinhan Nam, Tapani K Koppinen, Merja H Voutilainen. Frontiers in cellular neuroscience. 2021 Jul;15:640084.
PubMed: 34305531 · PMC: PMC8292680
MANF protein expression is upregulated in immune cells in the ischemic human brain and systemic recombinant MANF delivery in rat ischemic stroke model demonstrates anti-inflammatory effects. Jenni E Anttila, Olli S Mattila, Hock-Kean Liew, Kert Mätlik, Eero Mervaala, Päivi Lindholm, Maria Lindahl, Perttu J Lindsberg, Kuan-Yin Tseng, Mikko Airavaara. Acta neuropathologica communications. 2024 January;12:10.
PubMed: 38229173 · PMC: PMC10792833
