LSBio
IHC-plus™ LASS5 Antibody

Anti-LASS5 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

IHC-plus™ LASS5 Antibody

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunofluorescence, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse, Rat
Format:Liquid
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$470.00each
Catalog Number: LS-B3152-0.05

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Overview

Description
LASS5 antibody LS-B3152 is an unconjugated rabbit polyclonal antibody to LASS5 from human. It is reactive with human, mouse and rat. Validated for ELISA, IF, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IF, IHC, IHC-P, WB
Reactivity
Hu, Ms, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
Ceramide synthase 5 | CERS5 | LASS5 | Trh4
Recommended Dilution: IHC-P
5 µg/ml
Recommended Dilution: WB
1 - 2 µg/ml
UniProt Number
Q8N5B7
NCBI GenBank
NP_671723.1
SwissProt
Q8N5B7

Target

Target
LASS5
Antigen Species
Human
Specificity
Multiple isoforms of LASS5 are known to exist. This antibody may cross-react with the highly homologous LASS6.
Epitope
Multiple isoforms of LASS5 are known to exist. This antibody may cross-react with the highly homologous LASS6.
Gene Name
CERS5

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A 17 AA synthetic peptide near the C-Terminus of human LASS5. The immunogen is located within the last 50 AA of LASS5.
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS containing 0.02% Sodium Azide
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Store at 4°C for up 3 months. Store at -20°C for up to 1 year. Avoid freeze/thaw cycles.
Recommended Storage Buffer
PBS
High CerS5 expression levels associate with reduced patient survival and transition from apoptotic to autophagy signalling pathways in colorectal cancer. Fitzgerald S, Sheehan KM, Espina V, O'Grady A, Cummins R, Kenny D, Liotta L, O'Kennedy R, Kay EW, Kijanka GS. The journal of pathology Clinical research. 2015;1:54-65. PubMed: 27499893 PMC: PMC4858121

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