LSBio
IHC-plus™ ITGB1 / Integrin Beta 1 / CD29 Antibody (clone HUTS-4)

Anti-Integrin Beta 1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ ITGB1 / Integrin Beta 1 / CD29 Antibody (clone HUTS-4)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Flow Cytometry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Other, Western Blot
Reactivity:Human, Rat
Format:Liquid
See all ITGB1 / Integrin Beta 1 / CD29 antibodies →
$495.00each
Catalog Number: LS-B2861-50

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Overview

Description
CD29 antibody LS-B2861 is an unconjugated mouse monoclonal antibody to CD29 (ITGB1 / Integrin Beta 1) from human. It is reactive with human and rat. Validated for ELISA, Flow, IHC and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Application
ELISA, FC, IHC, IHC-P, Other, WB
Reactivity
Hu, Rt
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
CD29 | CD29 antigen | Integrin beta-1 | ITGB1 | MDF2 | MSK12 | Integrin VLA-4 beta subunit | VLA-BETA | VLAB | Beta 1 integrin | FNRB | GPIIA | Integrin Beta 1 | VLA-4 subunit beta
Recommended Dilution: IHC-P
10 µg/ml
UniProt Number
P05556
SwissProt
P05556

Target

Target
ITGB1 / Integrin Beta 1 / CD29
Antigen Species
Human
Specificity
Binds the active conformation of human, rat beta 1 integrins. Does not augment the affinity of beta 1 for ligands
Epitope
Specific for active conformation of human b1 integrins. Does not augment the affinity of beta 1 for ligands. Species cross-reactivity: rat.
Gene Name
ITGB1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
HUTS-4
Origin Species
Human

Immunogen

Immunogen
Human b1 integrins purified from Triton X-100 lysates of human lung, liver, and skeletal muscle tissues. Specifically selected due to its increased reactivity with T-lymphoblasts upon Mn2+ stimulation.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.1. No preservatives.
Concentration
1 mg/mL
Animal Free
No
Carrier-Free
Yes
Preservative
No
Purification Method
Other

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS

Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity. Du J, Chen X, Liang X, Zhang G, Xu J, He L, Zhan Q, Feng XQ, Chien S, Yang C. Proceedings of the National Academy of Sciences of the United States of America. 2011;108:9466-71.

PubMed: 21593411 · PMC: PMC3111285


Molecular mechanisms of the angiogenic effects of low-energy shock wave therapy: roles of mechanotransduction. Hatanaka K, Ito K, Shindo T, Kagaya Y, Ogata T, Eguchi K, Kurosawa R, Shimokawa H. American journal of physiology. Cell physiology. 2016;311:C378-85.

PubMed: 27413171

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