LSBio
IHC-plus™ IREB2 / IRP2 Antibody (aa100-200)

Anti-IREB2 antibody IHC of human brain. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

IHC-plus™ IREB2 / IRP2 Antibody (aa100-200)

Primary AntibodyLSBio Guarantee
Antibody:Rabbit Polyclonal
Applications:Immunocytochemistry, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Western Blot
Reactivity:Human, Mouse
Format:Liquid
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$383.00each
Catalog Number: LS-B48-0.1

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Overview

Description
IRP2 antibody LS-B48 is an unconjugated rabbit polyclonal antibody to IRP2 (IREB2) (aa100-200) from mouse. It is reactive with human and mouse. Validated for ICC, IHC and WB. Cited in 1 publication.
Application
ICC, IHC, IHC-P, WB
Reactivity
Hu, Ms
Predicted Reactivity
Rat
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee. ✓
Category
Antibodies > Primary Antibodies > Polyclonal Antibodies
Alternative Names
ACO3 | IREB2 | Iron regulatory protein 2 | IRP2AD | IRE-BP 2 | IRP2
Recommended Dilution: IF/ICC
1:500
Recommended Dilution: IHC-P
20 µg/ml
Recommended Dilution: WB
2 µg/ml
UniProt Number
P48200
NCBI GenBank
NM_004136
SwissProt
P48200

Target

Target
IREB2 / IRP2
Antigen Species
Mouse
Specificity
Rabbit Polyclonal to IRP2.
Epitope
Rabbit Polyclonal to IRP2.
Gene Name
IREB2

Antibody

Host Species
Rabbit
Clonality
Polyclonal
Origin Species
Human

Immunogen

Immunogen
A synthetic peptide made to an internal portion of the murine IRP2 protein sequence (between residues 100-200). UniProt Q811J3. Percent identity by BLAST analysis: Human, Primate, Rat (94%).
Immunogen Type
Synthetic Peptide (Linear)

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
Tris-Glycine, 150 mM NaCl, 0.05% Sodium Azide
Concentration
1.15 mg/mL
Volume
0.1 Milliliter
Animal Free
No
Carrier-Free
Yes
Preservative
Yes
Purification Method
Affinity Purified

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
Tris-Glycine, 150 mM NaCl
Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice. Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabón MA, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, Chen ZH, Goldklang MP, Yuan GC, Moore SC, Demeo DL, Rouault TA, D'Armiento JM, Schon EA, Manfredi G, Quackenbush J, Mahmood A, Silverman EK, Owen CA, Choi AM. Nature medicine. 2016;22:163-74. PubMed: 26752519 PMC: PMC4742374
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