LSBio
IHC-plus™ IL1R1 Antibody (Extracellular Domain, clone IL1-31-22.2.1)

Anti-IL1R1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.

IHC-plus™ IL1R1 Antibody (Extracellular Domain, clone IL1-31-22.2.1)

Primary AntibodyLSBio Guarantee
Antibody:Mouse Monoclonal
Applications:Enzyme-Linked Immunosorbent Assay, Immunohistochemistry (general), Immunohistochemistry, Paraffin, Radioimmunoassay
Reactivity:Human
Format:Liquid
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$470.00each
Catalog Number: LS-B2859-50

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Overview

Description
IL1R1 antibody LS-B2859 is an unconjugated mouse monoclonal antibody to human IL1R1 (Extracellular Domain). Validated for ELISA, IHC and RIA. Tested on 20 paraffin-embedded human tissues. Cited in 1 publication.
Application
ELISA, IHC, IHC-P, RIA
Reactivity
Hu
Intended Use
Research Use Only
Guarantees
This product carries the LSBio 100% Guarantee.
Category
Antibodies > Primary Antibodies > Monoclonal Antibodies
Alternative Names
Antigen CD121a | D2S1473 | IL-1R-1 | IL-1R-alpha | IL-1RT-1 | IL-1RT1 | IL1R | IL1R1 | IL1RA | IL1RT1 | Interleukin receptor 1 | Interleukin-1 receptor alpha | Interleukin-1 receptor type 1 | CD121A | CD121a antigen | Interleukin 1 receptor, type I | Interleukin-1 receptor type I | Interleukin-1 type i receptor | p80
Recommended Dilution: IHC-P
10 µg/ml
UniProt Number
P14778
SwissProt
P14778

Target

Target
IL1R1
Antigen Species
Human
Specificity
These antibodies react with cell surface and soluble human IL-1 receptor; Specific epitopes are unknown, but they do partially inhibit (30-50%) binding of one another to IL-1 receptor. They do not block binding of IL-1 to receptor, and they do not cross-react with receptors for human IL-2 or IL-4.
Epitope
These antibodies react with cell surface and soluble human IL-1 receptor; Specific epitopes are unknown, but they do partially inhibit (30-50%) binding of one another to IL-1 receptor. They do not block binding of IL-1 to receptor, and they do not cross-react with receptors for human IL-2 or IL-4.
Gene Name
IL1R1

Antibody

Host Species
Mouse
Clonality
Monoclonal
Clone
IL1-31-22.2.1
Origin Species
Human

Immunogen

Immunogen
The extracellular domain of the type I human IL-1 receptor.

Format

Conjugate/Label
Unconjugated
Format
Liquid
Formulation
PBS, pH 7.4
Concentration
1.45 mg/mL
Animal Free
No
Carrier-Free
Yes
Purification Method
Protein G Affinity

Storage & Handling

Storage Conditions
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Recommended Storage Buffer
PBS
The role of interleukin-1ß in human trophoblast motility. Prutsch N, Fock V, Haslinger P, Haider S, Fiala C, Pollheimer J, Knöfler M. Placenta. 2012;33:696-703. PubMed: 22710193

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